Tuscano Reviews Treatment and Toxicity Management for a Patient With Classic Hodgkin Lymphoma
April 5th 2021Assessing prognosis is an important step prior to treatment selection for a patient with classic Hodgkin lymphoma, explained Joseph Michael Tuscano, MD. Other steps aid in the treatment and management of toxicity.
Multiple Trial Regimens Demonstrate Efficacy for RET-Mutated Medullary Thyroid Cancer
March 31st 2021A number of clinical trials have provided evidence of efficacy of combination regimens for the treatment of RET-mutant medullary thyroid cancer. During a virtual Targeted Oncology Case-based Roundtable event, Lori Wirth, MD, discussed the options for a 58-year-old man with RET-mutant medullary thyroid cancer.
Experts Contemplate Realistic Treatment Goals Using Hedgehog Inhibitors in Basal Cell Carcinoma
March 26th 2021Hedgehog inhibitors are becoming more widely used for Basal cell carcinoma. Two experts, Shailender Bhatia, MD and Paul T. Nghiem, MD, PhD discussed the reality of hedgehog inhibitor use in practice during a virtual Targeted Oncology Case-Based Roundtable event.
Avelumab Maintenance Considered for a Patient With Metastatic Urothelial Cancer
March 9th 2021During a virtual Targeted Oncology Case-Based Roundtable event, Anish B. Parikh, MD, discussed front-line treatment options for metastatic urothelial cancer as well as the data supporting avelumab maintenance.
CARD Trial Data Show Efficacy for Metastatic Castration-Resistant Prostate Cancer
March 6th 2021During a Targeted Oncology virtual Case-Based Roundtable event, William K. Oh, MD, reviewed the data from the CARD trial as he shared the case of a 75-year-old man with metastatic castration-resistant prostate cancer (mCRPC) with a group of peers.
Brentuximab Vedotin Plus Chemotherapy Works as a Primary Option for Hodgkin Lymphoma
March 5th 2021Pierluigi Porcu, MD, explained how the combination of brentuximab vedotin plus chemotherapy works in in frontline setting of Hodgkin lymphoma during a virtual Targeted Oncology Case-Based Roundtable event.
PD-L1 Status Affects Physician’s Choice of Treatment in Lung Cancer
February 13th 2021For the treatment of patients with lung cancer and low PD-L1 expression, immunotherapy-based combinations have been shown effective through clinical trial research. Stephen Liu, MD, reviewed the studies during a Targeted Oncology Case-Based Peer Perspectives virtual event.
FDA Approves Trilaciclib to Reduce Chemotherapy-Induced Bone Marrow Suppression for ES-SCLC
February 12th 2021The FDA has approved trilaciclib (Cosela) as a first-in-class agent to help reduce the frequency of chemotherapy-induced bone marrow suppression in adults receiving chemotherapy for extensive-stage small cell lung cancer.
FDA Approves Liso-Cel CAR T-Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma
February 5th 2021The FDA has granted approval to lisocabtagene maraleucel a CD19-targeting chimeric antigen receptor T-cell therapy, for the treatment of adult patients with relapsed or refractory large B-cell lymphoma who have received at least 2 prior lines of systemic therapy.
Emerging Prognostic Tools for Myelofibrosis Further Refine Disease Status
February 2nd 2021Raajit K. Rampal, MD, PhD, hematologic oncologist, Memorial Sloan Kettering Cancer Center, reviewed the prognostic tools used to find indicators of response to treatment in patients with myelofibrosis, during a Targeted Oncology Case-Based Peer Perspective Roundtable discussion.
Rabinowits Analyzes the Use of Anti–PD-1 Therapy in cSCC
February 1st 2021During a Targeted Oncology Case-Based Peer Perspectives event, Guilherme Rabinowits, MD, medical oncologist/hematologist, Miami Cancer Institute, discussed the case of 69-year-old patients with cutaneous squamous cell carcinoma.
Maintenance Therapy With Atezolizumab Triplet Improves Survival in ES-SCLC
January 31st 2021The combination of atezolizuma plus carboplatin and etoposide demonstrated improvement in overall survival and progression-free survival when given as maintenance therapy to patients extensive stage small cell lung cancer, according to the latest findings from the IMpower 133 trial.
Evidence Supports BTK Inhibition in Chronic Lymphocytic Leukemia
January 28th 2021The role of Bruton's tyrosine kinase inhibitors in chronic lymphocytic leukemia is supported by clinical trial research. During a Targeted Oncology Case-Based Peer Perspectives Roundtable event, Peter Hillmen, MB ChB, PhD, provided evidence around acalabrutinib for the case of a 61-year-old woman.