LIBRETTO-001 and ARROW Trials Show Positive Data in RET Fusion–Positive Lung Cancer
April 28th 2021Jessica Bauman, MD, reviewed data from the LIBRETTO-001 and ARROW trials which show the efficacy and safety of selpercatinib and pralsetinib for the treatment of patients with RET fusion-positive lung cancer.
FDA Accelerates Approval of Sacituzumab Govitecan in Locally Advanced or Metastatic UC
April 13th 2021An accelerated approval was granted by the FDA to sacituzumab govitecan for the treatment of patients with locally advanced or metastatic urothelial cancer who previously received a platinum-containing chemotherapy and either a PD-1 or PD-L1 inhibitor.
Afatinib Shows Encouraging Efficacy and Safety in Late Stage EGFR-Mutant NSCLC
April 8th 2021Integrating afatinib into standard-of-care chemoradiation with or without surgery demonstrated encouraging efficacy, feasibility, and safety results in patients with stage III EGFR-mutation positive non–small cell lung cancer.
Tuscano Reviews Treatment and Toxicity Management for a Patient With Classic Hodgkin Lymphoma
April 5th 2021Assessing prognosis is an important step prior to treatment selection for a patient with classic Hodgkin lymphoma, explained Joseph Michael Tuscano, MD. Other steps aid in the treatment and management of toxicity.
Multiple Trial Regimens Demonstrate Efficacy for RET-Mutated Medullary Thyroid Cancer
March 31st 2021A number of clinical trials have provided evidence of efficacy of combination regimens for the treatment of RET-mutant medullary thyroid cancer. During a virtual Targeted Oncology Case-based Roundtable event, Lori Wirth, MD, discussed the options for a 58-year-old man with RET-mutant medullary thyroid cancer.
Experts Contemplate Realistic Treatment Goals Using Hedgehog Inhibitors in Basal Cell Carcinoma
March 26th 2021Hedgehog inhibitors are becoming more widely used for Basal cell carcinoma. Two experts, Shailender Bhatia, MD and Paul T. Nghiem, MD, PhD discussed the reality of hedgehog inhibitor use in practice during a virtual Targeted Oncology Case-Based Roundtable event.
Avelumab Maintenance Considered for a Patient With Metastatic Urothelial Cancer
March 9th 2021During a virtual Targeted Oncology Case-Based Roundtable event, Anish B. Parikh, MD, discussed front-line treatment options for metastatic urothelial cancer as well as the data supporting avelumab maintenance.