Carducci Discusses CARD Trial Data for Metastatic Castration-Resistant Prostate Cancer
May 12th 2021During a virtual Targeted Oncology Case-Based Roundtable event, Michael A. Carducci, MD, reviewed the results of the CARD trial to support his recommendation of cabazitaxel for the treatment of a 75-year-old man with metastatic castration-resistant prostate cancer.
Talazoparib May Be Most Optimal for Patients with Germline or Homozygous tDDR-altered mCRPC
May 9th 2021According to findings from a subgroup analysis of the TALAPRO-1 trial, men with heavily pretreated metastatic castration-resistant prostate cancer, with germline and/or homozygous tumor DNA damage response alterations are most likely to respond to talazoparib.
LIBRETTO-001 and ARROW Trials Show Positive Data in RET Fusion–Positive Lung Cancer
April 28th 2021Jessica Bauman, MD, reviewed data from the LIBRETTO-001 and ARROW trials which show the efficacy and safety of selpercatinib and pralsetinib for the treatment of patients with RET fusion-positive lung cancer.
FDA Accelerates Approval of Sacituzumab Govitecan in Locally Advanced or Metastatic UC
April 13th 2021An accelerated approval was granted by the FDA to sacituzumab govitecan for the treatment of patients with locally advanced or metastatic urothelial cancer who previously received a platinum-containing chemotherapy and either a PD-1 or PD-L1 inhibitor.
Afatinib Shows Encouraging Efficacy and Safety in Late Stage EGFR-Mutant NSCLC
April 8th 2021Integrating afatinib into standard-of-care chemoradiation with or without surgery demonstrated encouraging efficacy, feasibility, and safety results in patients with stage III EGFR-mutation positive non–small cell lung cancer.