Discontinuation or Continuation of IO Therapy – IO/IO vs. IO/TKI Regimens

Opinion
Video

Dr. Campbell evaluates the efficacy and safety results from the 55-month analysis of the CheckMate-9ER trial, and explores the considerations for discontinuing or continuing immunotherapy (IO) in IO/IO versus IO/TKI combination regimens.

  1. Dr Campbell: Please briefly review key efficacy and safety data from the CheckMate-9ER trial 55 month analysis (Bourlon MT, et al. 2024 ASCO Annual Meeting. Abstract 362).
    • What are the clinical implications of these data for treatment-naïve patients with advanced RCC?
    • In responders, how important is the durability of the response (OS and PFS) for both the intermediate/poor and favorable-risk groups?

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