Review of KEYNOTE-426: Five-year Follow-up Data
The key opinion leaders examine the data from the KEYNOTE-426 trial, focusing on safety and efficacy outcomes along with other pertinent updates.
EP: 1.Current treatment options for ccRCC based on patient and disease factors
EP: 2.CheckMate-214: Long-term follow-up data
EP: 3.Review of CheckMate-214: Long-term follow-up in favorable risk subgroup
EP: 4.Review of CLEAR and CheckMate-9ER: Four-Year and 55 Month Follow-Up Data
EP: 5.Review of KEYNOTE-426: Five-year Follow-up Data
EP: 6.Discontinuation or Continuation of IO Therapy – IO/IO vs. IO/TKI Regimens
EP: 7.Treatment-free survival in IO/TKI
EP: 8.Biomarkers: Impact on Treatment Choices and Future Expectations
EP: 9.Management of Adverse Events – IO/IO and IO/TKI
EP: 10.New formulations for current therapies – SC vs. IV
EP: 11.Novel Agents/Combinations for aRCC
- Dr McKay: Please briefly review key efficacy and safety data from the KEYNOTE-426 trial 5-year final analysis (Plimack et al. Eur Urol. 2023)?
- What are the clinical implications of these data for treatment-naïve patients with advanced RCC?
- In responders, how important is the durability of the response (OS and PFS) for both the intermediate/poor and favorable-risk groups?
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