Balancing Treatment Intensity and Resistance Mechanisms in First-Line EGFR-mutated NSCLC: Amivantamab + Lazertinib vs Osimertinib Monotherapy

Opinion
Video

The panelist discusses how, Healthcare professionals use osimertinib 1L for EGFR-mutated NSCLC, re-testing at progression for resistance mutations. MARIPOSA data refine 1L choices by predicting resistance pathways, guiding optimal sequencing.

Video content above is prompted by the following:

  • What is your sequencing strategy/rationale for 1L and beyond in EGFR-mutated metastatic NSCLC?
  • When would you re-test for new resistance mutations?
  • How does recent evidence from MARIPOSA (resistance mechanisms analysis) influence what you would use upfront in 1L treatment?
Recent Videos
1 expert in this video
1 expert in this video
1 KOL is featured in this series.
4 experts are featured in this series.
4 experts are featured in this series.
4 experts are featured in this series.
4 experts are featured in this series.
Related Content