First-Line Combination Therapy for EGFR-mutated Metastatic NSCLC: Evaluating Amivantamab + Lazertinib and Osimertinib-Based Regimens.

Opinion
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The panelist discusses how, regarding the patient case, she will review the FDA approved options for the patient, including the combination of amivantamab + Lazertinib, osimertinib/chemotherapy, or single agent osimertinib.

Video content above is prompted by the following:

  • Please discuss a treatment approach for the patient case.
  • Please review the evidence from MARIPOSA (amivantamab + lazertinib) and FLAURA2 (osimertinib/chemotherapy) supporting combination therapy in this setting.
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