ESA-Ineligible LR MDS patient with Transfusion-Dependent Anemia
Clinical Presentation:
74-year-old man diagnosed 6 months ago with LR-MDS with low-moderate anemia (Hb 11.4 g/dL)
Non-del(5q)
No family history of cancer or significant genotoxic agent exposure
Serum EPO – 550m U/L, Ring sideroblast (RS) negative
Hgb: 10.2 g/dL.
WBC and ANC: WNL
IPSS-R: Low
Received 2-3 units of blood every month for 4 months.
Treatment with ESAs is not an option due to his high serum EPO.
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