Please discuss the efficacy and safety findings from IMerge in patients for patients who have sermon EPO levels >500m U/L (ESA ineligible): IMerge (Platzbecker et al. Lancet 2024) (Santini et al. EHA 2024, Abstr. S184) MEDALIST (Fenaux et al. NEJM 2020) (Santini et al. ASH 2023, Abstr. 915)