Zolbetuximab and mFOLFOX6 Survival in CLDN18.2+ Advanced Gastric/GEJ Adenocarcinoma
January 20th 2023The combination of zolbetuximab and mFOLFOX6 prolonged survival in patients with CLDN18.2+ advanced gastric gastroesophageal junction adenocarcinoma, according to the phase 3 data from the SPOTLIGHT trial.
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CheckMate 648 trial of Nivolumab Plus Ipilimumab or Chemo in ESCC Continues to Show Survival Benefit
January 20th 2023Nivolumab with chemotherapy or ipilimumab continued to have a clinically meaningful survival benefit vs with chemotherapy alone in patients with treatment-naïve advanced esophageal squamous cell carcinoma.
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Single Agent Belantamab Mafodotin Shows Deep and Durable Responses in Final Analysis of RRMM Study
December 12th 2022In a final analysis of the DREAMM-2 study, results showed the rapid and durable responses of belantamab mafodotin continued in patients with relapsed/refractory multiple myeloma despite ocular toxicities.
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Acalabrutinib Appears to Have Quicker Time to Next Therapy Than Ibrutinib in Patients With CLL
December 12th 2022Patients with chronic lymphocytic leukemia on frontline acalabrutinib were more likely to switch to another therapy or intensify their treatment earlier on, compared to those on ibrutinib, according to real-world study data.
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Belantamb Mafodotin Shows PFS Benefit and Tolerable Safety in R/R Multiple Myeloma
December 12th 2022Compared with standard of care regimens for triple-class exposed, relapsed or refractory multiple myeloma, belantamb mafodotin with pomalidomide and dexamethasone extended progression-free survival without sacrificing safety.
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PROs Data Support Use of Upfront Daratumumab Quadruplet for Transplant Eligible, Newly-Diagnosed MM
December 12th 2022Encouraging health-related quality of life benefit was demonstrated in for patients with transplant eligible, newly diagnosed multiple myeloma treated with a daratumumab quadruplet regimen.
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Lenalidomide/ Rituximab Extends 5-Year PFS on R/R Indolent Non-Hodgkin Lymphoma
December 11th 2022Five-year follow up results from the phase 3 AUGMENT trial show that lenalidomide plus rituximab produced enhanced progression-free survival in patients with relapsed/refractory indolent non-Hodgkin lymphoma.
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