November 20th 2024
During a Case-Based Roundtable® event, Omar Nadeem, MD, and participants reacted to data from the MonumenTAL-1 trial in the first article of a 2-part series.
Gamma Secretase Inhibitor Improves Responses to BCMA CAR T Cells in Myeloma
January 14th 2020In an interview with Targeted Oncology, Andrew J. Cowan, MD, discussed the findings from the first-in-human clinical trial evaluating the combination of a GSI and BCMA CAR T cells in patients with heavily pretreated multiple myeloma. He highlighted the next steps for this research and how he sees CAR T-cell therapy evolving over the coming years.
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Ibrutinib Triplet Elicits Clinical Responses in Pretreated Myeloma Before Study Termination
January 11th 2020Results from a phase II, open-label, multicenter study have shown that patients with heavily pretreated multiple myeloma responded to ibrutinib combined with bortezomib (Velcade) and dexamethasone.
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Daratumumab Plus Rd Sustains Responses in Transplant-Ineligible Myeloma
January 4th 2020In an interview with Targeted Oncology, Nizar Bahlis, MD, discussed the updated findings from the MAIA trial, which he presented at the 2019 ASH Annual Meeting. He highlighted the updates to the PFS, OS, and overall response rate data, as well as some other areas daratumumab is under investigation now following the positive data from this trial.
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