Targeted Oncology reviews trending news online for the week of September 18, 2020, including updates in oncology, and new information regarding COVID-19.
This week, the FDA granted a Fast Track designation to the novel androgen receptor EPI-7386 as treatment of adult patients with metastatic castration-resistant prostate cancer who are resistant to standard of care treatment. A Breakthrough Therapy designation was also granted to magrolimab as treatment of patients with newly diagnosed myelodysplastic syndrome.
The Society of Hematologic Oncology (SOHO) hosted its eighth annual virtual meeting, in which attendance nearly doubled compared with previous years. The meeting focused on a theme of Molecular Classification and Precision Therapy with more than 150 presentations on a variety of hematologic malignancies.
Check out conference coverage from the ESMO Virtual Congress 2020.
Pennell Examines Targeted Therapies in EGFR-Mutated NSCLC
Nathan A. Pennell, MD, PhD, discussed the case of 66-year-old patient with EGFR-mutant non–small cell lung cancer, during a virtual Case Based Peer Perspectives event.
HER2+ Breast Cancer Treatment Approaches Becomes More Individualized
In an interview with Targeted Oncology, Sara A. Hurvitz, MD, reviewed the 4 currently approved treatment options for patients with HER2-positive breast cancer and discussed how physicians could use the data to make treatment decisions in the adjuvant and neoadjuvant setting.
Ibrutinib and Venetoclax Under Investigation as First-Line Combo in MCL
The combination of ibrutinib (Imbruvica) and venetoclax (Venclexta) will be tested as frontline therapy in previously untreated patients with mantle cell lymphoma as part of the 3-part phase 3 SYMPATICO trial.
Lymphoma Treatment Paradigm Refined Over Years, Expert Says on World Lymphoma Awareness Day
In an interview with Targeted Oncology, Thomas M. Habermann, MD, reflects on the advancements he has observed in the treatment paradigm for lymphomas.
Black Patients Experience Lower OS With CRC Liver Metastases Than Others
Compared to other racial and ethnic groups, Black patients were the least likely to receive chemotherapy or surgical resection for colorectal liver metastases and experienced worse survival
Ruxolitinib Appears Effective as Treatment of Steroid-Refractory GVHD
Uday R. Popat, MD, discusses the role of the JAK inhibitor ruxolitinib (Jakafi) as treatment of patients with graft-versus-host-disease.
Case-Based Peer Perspectives: A 73-Year-Old Man With Urothelial Carcinoma
Neeraj Agarwal, MD, reviews the case of a 73-year-old man with unresectable, locally advanced urothelial carcinoma and discusses latest data and treatment approaches.
More Analysis Is Needed of COVID-19, Cancer Interactions
As COVID-19 alters current approaches to caring for patients with cancer, early emerging research data reinforce what practicing oncologists have been observing in their patients are at increased risk of mortality.
Navigating ESR1 Mutations in HR-Positive Breast Cancer With Dr Wander
October 31st 2024In this episode of Targeted Talks, Seth Wander, MD, PhD, discusses the clinical importance of ESR1 mutations in HR-positive metastatic breast cancer and how these mutations influence treatment approaches.
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