The Week of May 6 in Review
The week of May 6 in review, featuring stories and videos on cabozantinib in medullary thyroid cancer, biomarkers in prostate cancer, and SAR302503 in myelofibrosis.
Dr. Landgren on the Standard of Care for Myeloma in 2013
Dr. Petrylak on Biomarker Discovery in Advanced Prostate Cancer
Mechanism of Action: Cetuximab
Penny Daugherty Comments on the Presence of a BRCA Mutation
Dr. Piccart on the Changing View of Anti-HER2 Therapies
TweetOla Landgren, MD, PhD, Head, Multiple Myeloma Section, National Cancer Institute, discusses the standard of care for myeloma in 2013.Daniel P. Petrylak, MD, director, Prostate and Genitourinary Cancer Program, co-director, Signal Transduction Research Program, at the Smilow Cancer Center at Yale-New Haven, discusses potential biomarkers currently being explored in castration-resistant prostate cancer (CRPC).Cetuximab is an epidermal growth factor receptor inhibitor used for the treatment of metastatic colorectal cancer and head and neck cancer.Penny Daugherty, RN, MS, OCN, Southeastern Gynecologic Oncology, comments on the presence of a BRCA mutation in her patients.Martine Piccart, MD, PhD, director of medicine at the Jules Bordet Institute in Brussels, Belgium, discusses the changing view of anti-HER2 therapies for patients with breast cancer.
Cabozantinib in Medullary Thyroid Cancer
Dr. Howard Scher on Findings From the COU-AA-302 Trial
PI3K Inhibitors in Breast Cancer Treatment
Dr. Zaks Describes the Mechanism of Action of SAR302503
Turning Concept Into Reality: Modulating the Immune System to Treat NSCLC
Dr. Leonard Gomella on Utilizing CTCs in Solid Tumors
Cabozantinib is a novel, small-molecule, multitargeted receptor tyrosine kinase inhibitor with particular activity against MET, VEGFR-2, and RET.Howard I. Scher, MD, Chief of the Genitourinary Oncology Service at the Sidney Kimmel Center for Prostate and Urologic Cancers at Memorial Sloan-Kettering Cancer Center, discusses an updated analysis of the COU-AA-302 trial.Aberrant activation of the PI3K pathway occurs frequently in breast cancer and contributes to treatment resistance to standard therapy.Tal Zaks, MD, PhD, vice president and head of development at Sanofi Oncology, explains the mechanism of action of SAR302503, a tyrosine kinase inhibitor being investigated in a phase III trial in patients with intermediate-2 or high-risk myelofibrosis.For many years nonsmall cell lung cancer (NSCLC), unlike melanoma and renal cell carcinoma, was thought to be a nonimmunogenic tumor unlikely to benefit from therapies aimed at augmenting endogenous antitumor immunity.
Improving the Transition From Inpatient to Outpatient Care in Oncology
November 27th 2024A recent Targeted Oncology survey explores the challenges and best practices in transitioning patients with cancer from inpatient to outpatient care, featuring insights from Cristina Gasparetto, MD, on improving these processes.
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Phase 1b/2 Study of BXQ-350 in Metastatic Colorectal Cancer Completes Enrollment
November 27th 2024Enrollment has been completed for the phase 1b/2 ASIST study that is evaluating BXQ-350 in combination with standard-of-care treatments in patients with newly diagnosed metastatic colorectal cancer.
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Navigating ESR1 Mutations in HR-Positive Breast Cancer With Dr Wander
October 31st 2024In this episode of Targeted Talks, Seth Wander, MD, PhD, discusses the clinical importance of ESR1 mutations in HR-positive metastatic breast cancer and how these mutations influence treatment approaches.
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