The Role of CD123 Targeted Therapy (tagraxofusp) in the Evolving Treatment Landscape for BPDCN

Opinion
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An expert discusses how medical professionals have integrated tagraxofusp into blastic plasmacytoid dendritic cell neoplasm (BPDCN) treatment, leveraging its CD123-targeted efficacy per 0114 trial data. Real-world findings (Angelucci et al, ASH 2023) align with clinical outcomes, reinforcing tagraxofusp’s role in BPDCN management by supporting its safety and effectiveness in broader settings.

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      Video content above is prompted by the following:

      • Given the efficacy/safety data from the 0114-trial evaluating tagraxofusp in BPDCN, how have you adapted your treatment approach to incorporate CD123 targeted therapy?
      • Do real-world data (Angelucci et al, ASH 2023) of tagraxofusp in BPDCN complement trial data?

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