Roundtable Roundup: First and Second Choices for Frontline RCC Therapy
During separate virtual live events, David A. Braun, MD, PhD, and Rana R. McKay, MD, surveyed oncologists on options for a patient with clear cell renal cell carcinoma (RCC) in the front line.
CASE SUMMARY
- A 59-year-old African American woman was diagnosed with a left renal mass.
- She underwent left radical nephrectomy in December 2019.
- Clear cell RCC
- T3aN0Mx, International Society of Urological Pathology grade 3
- Nine months later, she reported pain in hips and left chest.
- Radiographic diagnosis: stage IV RCC with osteolytic lesions in iliac crest and left fifth rib
- ECOG performance status: 1
- Laboratory results:
- Hemoglobin level: 11.1 g/dL
- Elevated liver function test results
- Mild hypercalcemia (10.8 mg/dL)
- Neutrophil and platelet counts: within normal limits
CASE UPDATE
The patient received nivolumab (Opdivo) plus ipilimumab (Yervoy).
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