High-Risk MIBC: Adjuvant Therapy Options After Radical Cystectomy

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An expert discusses how adjuvant therapy options for high-risk muscle-invasive bladder cancer (MIBC); ypT2-ypT4a or N+) include cisplatin-based chemotherapy, which improves survival by targeting micrometastatic disease. Immune checkpoint inhibitors, such as atezolizumab and nivolumab, offer alternatives for cisplatin-ineligible patients.

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  • What are the adjuvant therapy options for patients with high-risk muscle invasive bladder cancer (ypT2-ypT4a or N+)?
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