Saad Z. Usmani, MD, discusses the combination of carfilzomib and filanesib as a treatment for multiple myeloma.
Saad Z. Usmani, MD, director, Plasma Cells Disorder Program, Levine Cancer Institute/Carolinas Healthcare System, discusses the combination of carfilzomib and filanesib as a treatment for multiple myeloma. Usmani said a recent phase II study showcased a response rate of 14% in the carfilzomib-only arm, while a response rate of 35% was seen in the arm with patients receiving a combination of carfilzomib and filanesib.
Usmani said the regimen was efficacious, though the main question still persisting post study is how much dosing of carfilzomib should be included in an upcoming phase III study.
Ilson Examines Chemoimmunotherapy Regimens for Metastatic Gastroesophageal Cancers
December 20th 2024During a Case-Based Roundtable® event, David H. Ilson, MD, PhD, discussed the outcomes of the CheckMate 649, CheckMate 648, and KEYNOTE-859 trials of chemoimmunotherapy regimens in patients with upper GI cancers.
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Participants Discuss Frontline Immunotherapy Followed by ADC for Metastatic Cervical Cancer
December 19th 2024During a Case-Based Roundtable® event, Ramez N. Eskander, MD, and participants discussed first and second-line therapy decisions for a patient with PD-L1–positive cervical cancer in the frontline metastatic setting.
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Oncologists Discuss a Second-Generation BTK for Relapsed/Refractory CLL
December 18th 2024During a Case-Based Roundtable® event, Daniel A. Ermann, MD, discussed evaluation and treatment for a patient with relapsed chronic lymphocytic leukemia after receiving venetoclax and obinutuzumab.
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