Dr. Robert Z Orlowski on the Importance of the Phase III SWOG S0777 Trial
Data from the trial shows induction therapy with a triplet of bortezomib, lenalidomide, and dexamethasone improved both progression-free survival and overall survival over lenalidomide and dexamethasone alone in patients with untreated multiple myeloma.
Robert Z Orlowski, MD, PhD, professor, Department of Lymphoma/Myeloma, Division of Cancer Medicine, MD Anderson Cancer Center, on the importance of the SWOG S0777 trial. Data from the trial shows induction therapy with a triplet of bortezomib, lenalidomide, and dexamethasone improved both progression-free survival and overall survival over lenalidomide and dexamethasone alone in patients with untreated multiple myeloma.
Orlowski says oncologists have been using a combination of bortezomib, lenalidomide, and dexamethasone for years as thede factofrontline treatment, despite phase III trial data was not present. He says this is important for oncologists because the triplet now joins the Category 1 recommendation level from the National Comprehensive Cancer Network.
Real-World RRMM Data Explore Dose Deescalation and Outpatient Use of Teclistamab
November 18th 2024During a Case-Based Roundtable® event, Hana Safah, MD, examined several real-world studies of dose frequency and outpatient administration of teclistamab in patients with multiple myeloma in the first article of a 2-part series.
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