Case 1: IMpassion 130 Trial Design and Results
Experts in breast cancer discuss efficacy data from the IMpassion130 clinical trial.
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Case 1: 53-Year-Old Woman With TNBC
Elizabeth Mittendorf, MD, PhD, reviews the case of a 53-year-old woman with PD-L1+ TNBC breast cancer and the panel discusses relevant clinical trial data.
Case 2: Recurrence in High-Risk HR+/HER2+ Breast Cancer
Ingrid Mayer, MD, MSCI, presents the case of a patient with high-risk HR+/HER2+ breast cancer who develops recurrence after a long disease-free interval.
Best Therapies for HER2+ Breast Cancer Are Also Best for Brain Metastases
Thomas Bachelot, MD, PhD, discusses therapies available for patients with HER2-positive breast cancer and brain metastases.
Unmet Needs in Advanced or Metastatic TRK Fusion+ Thyroid Cancer
Marie E. Cabanillas, MD, an oncologic endocrinologist at the University of Texas MD Anderson Cancer Center, discusses current unmet needs in advanced or metastatic TRK fusion-Positive thyroid cancer.
Exploring Current and Future Treatment in Patients With DLBCL
Mitul Gandhi, MD, discusses the current landscape for patients with diffuse large B-cell lymphoma and what may be coming in the future.
monarchE Investigators Set Out to Make Practice-Changing Impact in Breast Cancer
Nadia Harbeck, MD, PhD, discusses how the monarchE trial, which evaluated the efficacy of endocrine therapy with or without abemaciclib, will change breast cancer treatment.
Future Directions and Unmet Needs in the Treatment of R/R FL
Looking ahead, Loretta Nastoupil, MD, reviews the future direction and unmet needs in the management of relapsed/refractory follicular lymphoma (R/R FL).
Managing Side Effects of Tazemetostat in R/R FL
Dr Loretta Nastoupil describes best practices for managing the side effects of tazemetostat in patients with R/R FL.
Efficacy of tazemetostat in patients with EZH2m and EZH2wt R/R FL
Loretta Nastoupil, MD, discusses the use of tazemetostat in patients with and without an EZH2m.
Treatment Challenges Beyond the Second-line in R/R FL
Loretta Nastoupil, MD, describes the challenges of selecting treatment beyond the second-line.
Second-line Treatment Options for R/R FL Patients
Considerations for Therapy in R/R FL
A key opinion leader in the treatment of FL provides insight on the decision of whether to add maintenance therapy to the treatment regimen.
First-line Therapy Options in ND Follicular Lymphoma
Loretta Nastoupil, MD, discusses first-line therapy options for patients with newly diagnosed follicular lymphoma (ND FL).
R/R FL Patient Case Review and Impressions
Loretta Nastoupil, MD, describes the role of molecular testing used in risk stratification of patient with FL
Case Presentation: Relapsed/Refractory Follicular Lymphoma
Loretta Nastoupil, MD, reviews the case of a 75-year-old woman with relapsed/refractory follicular lymphoma (R/R FL).
Clinical Trials with Early PI3K Inhibitors in R/R FL and MZL
Expert hematologist/oncologists discuss the use of early PI3K inhibitors in the management of R/R follicular lymphoma (FL) and MZL (marginal zone lymphoma).
Overview of PI3K Inhibition in Lymphoma
Ian W. Flinn, MD, PhD, leads the discussion on the various PI3K isoforms and their role in lymphoma.
Case 2: Considerations for Optimizing Therapy in High Risk MF
Ruben Mesa, MD, and panel discuss considerations for optimizing therapy in high risk myelofibrosis.
Case 2: Efficacy and Safety of Fedratinib in High Risk MF
Experts in myelofibrosis present safety and efficacy data from a clinical trial of fedratinib in patients with high risk myelofibrosis.
Case 2: Safety and Efficacy of Ruxolitinib in High Risk MF
Dr Jamile Shammo presents clinical trial data on the efficacy and safety of ruxolitinib in patients with high risk myelofibrosis.
Case 2: Predictors of Response to Ruxolitinib in High Risk MF
Experts in MPN review data on predictors of response to ruxolitinib in high risk myelofibrosis.
Case 2: Prognostic Models of MF
Jamile Shammo, MD, reviews prognostic models in myelofibrosis.
Case 2: High Risk Myelofibrosis (MF)
Dr Jamile Shammo reviews the case of a 72-year-old man with primary myelofibrosis.
Case 1: Novel Therapeutic Approaches in High-Risk, Early Stage HER2+ Breast Cancer
Experts in the management of breast cancer review some trials leading to the future of personalized treatment for HER2+ breast cancer.
Case 1: Assessment of Risk of Recurrence in HER2+ Breast Cancer
Andrew Seidman, MD, follows the patient after TCHP therapy and discusses the risk of recurrence with the experts.
Case 1: Subcutaneous HP Therapy in HER2+ Breast Cancer
Ingrid Mayer, MD, MSCI, and panel share the benefits of subcutaneous HP instead of IV HP therapy, particularly for the patients’ quality of life.
Case 1: Dual HER2-Targeted Therapy in HER2+ Early Breast Cancer
The panel of experts reviews the use dual HER2-targeted therapy in HER2+ breast cancer.
Case 1: Role of Anthracyclines in HER2+ Early Breast Cancer
Experts in breast cancer management discuss the use of anthracycline and risk of the cardiac toxicities.
Research Supporting the Use of Ruxolitinib for the Treatment of Myelofibrosis
Haris Ali, MD, discusses research supporting the use of ruxolitinib for the treatment of myelofibrosis.