Case 3: Treatment Options for CNS Progression in HER2+ Breast Cancer
Experts in the management of breast cancer discuss the role of tucatinib in patients with brain metastases.
Watch
Case 2: Considerations for PARP Inhibitor Use in TNBC
Experts in the management of breast cancer review some treatment considerations surrounding the use of PARP inhibitors in BRCA1/2–positive triple-negative breast cancer.
Case 2: 34-Year-Old Woman With TNBC
Elizabeth Mittendorf, MD, PhD, presents the case of a 34-year-old woman with PD-L1–positive triple-negative breast cancer.
Future of PI3K Inhibitors in RR FL and MZL
Expert hematologist/oncologists provide thoughts on the potential role of PI3K inhibitors in managing R/R FL and MZL, as well as other diseases.
Emerging Combinations and Novel Agents for RR FL and MZL
Ian W. Flinn, MD, PhD, and Jason M. Melear, MD, discuss the role of PI3K inhibitor combination therapy and novel agents on the horizon for the treatment of R/R FL and MZL.
Investigators Are Exploring Neoadjuvant and Adjuvant Therapy in HCC
Amit Singal, MD, discusses options after surgical resection for patients with hepatocellular carcinoma.
CAR T Cells Have Reshaped the Hematologic Cancer Landscape
Michael Bishop, MD, discusses the different settings where chimeric antigen receptor T-cell therapy are used.
Addressing Unmet Needs to Precision Medicine in EGFR Exon 20-Positive NSCLC
Joshua K. Sabari, MD, discusses the need for EGFR inhibitors designed specifically to treat patients with EGFR-mutant non–small cell lung cancer and an exon 20 insertion.
Unmet Needs and Future Directions in ES-SCLC
Jared Weiss, MD, shares insight into current unmet needs in extensive-stage small cell lung cancer and provides advice to researchers about the importance of clinical trials studying differential treatments and biomarkers.
The ATLANTIS Study of Lurbinectedin/Doxorubicin
Expert oncologist Jared Weiss, MD, considers safety and efficacy data from the ATLANTIS study of lurbinectedin in combination with doxorubicin in relapsed small cell lung cancer.
Safety and Efficacy of Lurbinectedin in Solid Tumors
Thought leader in lung cancer, Jared Weiss, MD, reviews safety and efficacy data from the phase 2 basket trial of lurbinectedin in selected advanced solid tumors.
Second-Line Treatment After Maintenance Immunotherapy
Key opinion leader in thoracic oncology, Jared Weiss, MD, discusses the role of second-line treatment for relapsed ES-SCLC after first-line therapy and maintenance immunotherapy.
First-Line Treatment Options for ES-SCLC
Jared Weiss, MD, reviews first-line treatment options for extensive-stage small cell lung cancer and highlights the current standard-of-care regimen: carboplatin, etoposide, and a PD-L1 inhibitor with the possible addition of trilaciclib.
Case Overview: A 64-Year-Old Woman With ES-SCLC
An expert in the management of lung cancer, Jared Weiss, MD, provides an overview of the initial presentation, clinical work-up, treatment, and follow-up of a 64-year-old woman with extensive-stage small cell lung cancer.
Danilov on BTK Inhibition for Relapsed/Refractory CLL
Alexey Danilov, MD, a hematologist oncologist at the City of Hope Comprehensive Cancer Center, discusses treatment options for relapsed/refractory chronic lymphocytic leukemia.
Case 3: Disease Progression and Transformation in ET
Stephen Oh, MD, PhD, discusses the nuances of identifying disease progression vs transformation in patients with essential thrombocythemia.
Case 3: Front Line Therapy Options in ET
Experts in essential thrombocythemia review first line treatment options.
Case 3: Molecular Profile and Initiation of Therapy in ET
Ruben Mesa, MD, and panel discuss the role of molecular profile in treatment decision-making.
Case 3: Individualized Therapy for ET
Experts in essential thrombocythemia discuss approaches to individualizing therapy.
Case 3: Risk Assessment in ET
Dr Stephen Oh discusses risk assessment in patients with essential thrombocythemia.
Case 3: Essential Thrombocythemia (ET)
Stephen Oh, MD, PhD, reviews the case of a 46-year-old female with essential thrombocythemia.
UNITY-NHL Trial in R/R FL and MZL
Experts in hematology/oncology review data from the UNITY-NHL trial and share insights on the sequencing of therapies in R/R FL and MZL.
Role of Umbralisib in R/R FL and MZL
Ian W. Flinn, MD, PhD, and Jason M. Melear, MD, review the tolerability and efficacy of umbralisib in the management of R/R FL and MZL.
Managing Adverse Events of PI3K Inhibitors in R/R FL and MZL
Expert hematologist/oncologists comment on the safety profile of PI3K inhibitors when treating R/R FL and MZL and share their approach to managing associated adverse events.
Role of PI3K Inhibitors in the Management of R/R FL and MZL
Ian W. Flinn, MD, PhD, and Jason M. Melear, MD, review clinical trial data for idelalisib, copanlisib, and duvelisib and discuss their personal experience using these agents for the management of R/R FL and MZL.
Age-Related Characteristics Impact Outcomes in AML
Rajneesh Nath, MD, discusses outcomes for older patients with acute myeloid leukemia.
Case 1: Treatment Recommendations for PD-L1+ TNBC
The panel discusses treatment options and considerations for a 53-year-old woman with PD-L1+ triple-negative breast cancer.
Case 2: Recurrence of HER2+ Breast Cancer After 12 Months
Carey Anders, MD, and Andrew Seidman, MD, share their recommendations for HER2+ breast cancer recurrence within 12 months of HP.
Case 1: KEYNOTE-355 Trial Design and Considerations
The panel of experts review the study design and key efficacy data of the KEYNOTE-355 trial.
Case 2: Treatment Options at Recurrence of HER2+ Breast Cancer After 5 Years
The panel of experts in breast cancer discuss treatment options when the cancer has metastasized.