Peter Voorhees, MD, investigator, department of hematologic oncology & blood disorders, Levine Cancer Institute/Atrium Health, discusses the rationale for adding daratumumab to triplet regimen bortezomib, lenalidomide, and dexamethasone in patients with multiple myeloma.
Peter Voorhees, MD, investigator, department of hematologic oncology & blood disorders, Levine Cancer Institute/Atrium Health, discusses the rationale for adding daratumumab (Darzalex) to the triplet regimen bortezomib (Velcade), lenalidomide (Revlimid), and dexamethasone (Dara-RVd) in patients with multiple myeloma.
In previous trials, RVd induction therapy performed well for both patients with transplant eligible disease as well as transplant ineligible, Voorhees says. In addition, the IFM 2009 trial showed that lenalidomide induction followed by transplant with lenalidomide consolidation and 1 year of lenalidomide maintenance demonstrated a complete response rate of 60% and median progression-free survival of 50 months.
Gasparetto Explains Rationale for Quadruplet Front Line in Transplant-Ineligible Myeloma
February 22nd 2025In a Community Case Forum in partnership with the North Carolina Oncology Association, Cristina Gasparetto, MD, discussed the CEPHEUS, IMROZ, and BENEFIT trials of treatment for transplant-ineligible newly diagnosed multiple myeloma.
Read More
Key Trials From ASH 2024 Impact Treatment for Plasma Cell Disorders Going Forward
February 20th 2025Peers & Perspectives in Oncology editorial board member Marc J. Braunstein, MD, PhD, FACP, discussed the significant advancements in multiple myeloma treatment at the 2024 ASH Annual Meeting and Exposition.
Read More