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Opinion|Videos|November 8, 2024

MARIPOSA-2: Second-Interim Survival Data

Author(s)Hatim Husain, MD

Panelist discusses how the second interim overall survival data from MARIPOSA-2, presented at the European Society for Medical Oncology Congress 2024, affect treatment strategies for patients with non–small cell lung cancer that has developed resistance to osimertinib.

Episodes in this series

1 KOL is featured in this series.

EP. 1 Acquired Resistance to Kinase Inhibitors - EGFR- mutated Non-Small Cell Lung Cancer

1 KOL is featured in this series.

EP. 2 Osimertinib: Evolution of Treatment from Refractory Disease to Prevention of Drivers of Disease Progression

1 KOL is featured in this series.

EP. 3 Mechanisms of Acquired Resistance in First-Line Treatment – Amivantamab plus Lazertinib vs. Osimertinib

1 KOL is featured in this series.

EP. 4 MARIPOSA-2: Second-Interim Survival Data

1 KOL is featured in this series.

EP. 5 Adverse Event Management: Amivantamab

1 KOL is featured in this series.

EP. 6 Future Treatment Landscape for EGFR-mutated Non-Small Cell Lung Cancer

Video content above is prompted by the following:

The second interim overall survival data from MARIPOSA-2 were presented at the European Society for Medical Oncology Congress 2024.

Please briefly discuss the updated data and the implications for second-line therapy for those currently receiving osimertinib, particularly when osimertinib is continued with platinum-based chemotherapy after resistance to osimertinib is noted.

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