KRAS G12C Emerges as New Potential Target in Non-Small Cell Lung Cancer
Edward B. Garon, MD, discusses an exciting new agent, or class of agents, that are under evaluation as treatment of patients with non-small cell lung cancer.
Edward B. Garon, MD, director of Thoracic Oncology at the Jonsson Comprehensive Cancer Center at University of California, Los Angeles, discusses an exciting new agent, or class of agents, that are under evaluation as treatment of patients with non-small cell lung cancer (NSCLC).
The class of agents Garon finds exciting in the field of NSCLC is the KRAS G12C inhibitors. These agents have generating a lot of enthusiasm as the KRAS mutation is a very trackable target, and KRAS also appears to be very prevalent in NSCLC. Garon says KRAS is similar to EGFR mutations in terms of prevalence in NSCLC.
There is new data emerging now and clinical trials evaluating this target in NSCLC, Garon adds. It will be exciting to see how these therapies evolve as treatment of patients with NSCLC who may harbor a KRAS mutation.
<<View data for a novel KRAS G12C inhibitor as treatment of multiple solid tumors
Advancing Neoadjuvant Therapy for HER2+ Breast Cancer Through ctDNA Monitoring
December 19th 2024In an interview with Targeted Oncology, Adrienne Waks, MD, provided insights into the significance of the findings from the DAPHNe trial and their clinical implications for patients with HER2-positive breast cancer.
Read More
AI-Driven Deep Learning Model Shows Promise in Standardizing MDS Diagnosis
December 10th 2024In an interview, Palak Dave discussed how artificial intelligence, using deep learning to analyze bone marrow aspirate smear images, could standardize and accelerate the diagnosis of MDS vs pre-MDS conditions.
Read More
Systemic Therapy Choice Linked to Radiosurgery Outcomes in Brain Mets
December 6th 2024In an interview with Targeted OncologyT, Rupesh Kotecha, MD, discussed a study focused on how systemic therapy selection impacts outcomes in patients with brain metastases, particularly those with lung cancer.
Read More
