Ghassan Abou-Alfa says serafnib is currently the only first-line treatment approved for HCC based on the SHARP trial, where the treatment showed improved survival in patients from 7.9 months to 10.7 months.
Ghassan Abou-Alfa, MD, medical oncologist, Memorial Sloan Kettering Cancer Center, talks about first- and second-line treatments for hepatocellular carcinoma (HCC). He says sorafenib is currently the only first-line treatment approved for HCC based on the SHARP trial, where the treatment showed improved survival in patients from 7.9 months to 10.7 months.
Abou-Alfa says he finds it interesting that second-line therapies are already being investigated despite there not being many options for first-line treatments. He says nivolumab and pembrolizumab may have a place in the treatment of HCC.
Survivorship Care Promotes Evidence-Based Approaches for Quality of Life and Beyond
March 21st 2025Frank J. Penedo, PhD, explains the challenges of survivorship care for patients with cancer and how he implements programs to support patients’ emotional, physical, and practical needs.
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