Colorectal Cancer

Unresectable Colon Cancer with Charles Fuchs, MD and Tanios Bekaii-Saab, MD

Unresectable Colon Cancer with Charles Fuchs, MD and Tanios Bekaii-Saab, MD

Treatment with the novel multikinase inhibitor entrectinib achieved objective responses in 79% of patients with solid tumors associated with NTRK, ROS-1, or ALK rearrangements.

Treatment with ensituximab (NPC-1C), a chimeric IgG1 monoclonal antibody, induced stable disease in nearly half of patients with chemotherapy-refractory metastatic colorectal cancer (mCRC) without contributing significant toxicity.

The protein NOD-like receptor X1 (NLRX1) could be a potential biomarker to predict response for treatments in patients with colorectal cancer (CRC), according to a study published in Cell Reports.

The addition of Yttrium-90 (Y-90) resin microspheres (SIR-Spheres) to standard frontline FOLFOX-based chemotherapy with or without bevacizumab significantly improved liver-specific progression-free survival (PFS) for patients with liver metastatic colorectal cancer (CRC), according to findings from the phase III SIRFLOX study published in the Journal of Clinical Oncology.

mCRC with Tanios Bekaii-Saab, MD and Tara Seery, MD