November 22nd 2024
A phase 1 trial of α-lactalbumin vaccine for the treatment of patients with triple-negative breast cancer demonstrated safety and tolerability.
November 21st 2024
42nd Annual CFS: Innovative Cancer Therapy for Tomorrow®
November 13-15, 2024
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Community Practice Connections™: 5th Annual Precision Medicine Symposium – An Illustrated Tumor Board
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Community Oncology Connections™: Controversies and Conversations About HER2-Expressing Breast Cancer… Advances in Management from HER2-Low to Positive Disease
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Emerging Treatments and Evolving Paradigms in HER2-Low Breast Cancer
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Matching the Right Patients to the Right Therapies in TNBC: Case-Based Applications of Immune Checkpoint Inhibitors, PARP Inhibitors, and TROP2-Targeted ADCs
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Matching the Right Patients to the Right Therapies in TNBC: Case-Based Applications of Immune Checkpoint Inhibitors, PARP Inhibitors, and TROP2-Targeted ADCs
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Clinical Vignettes™: The Experts Explain How They Integrate PET Imaging into Metastatic HR+ Breast Cancer Care Settings
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School of Breast Oncology® Live Video Webcast: Clinical Updates from San Antonio
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Annual Hawaii Cancer Conference
January 25-26, 2025
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41st Annual CFS®: Innovative Cancer Therapy for Tomorrow
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42nd Annual Miami Breast Cancer Conference®
March 6 - 9, 2025
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The Evolving Tool Box in Advanced HR+/HER2– Breast Cancer: What You Need to Know About Next-Generation SERDs, PI3K/AKT, ADCs, CDK4/6 and Beyond…
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Next-Generation Endocrine Therapy for ER+/HER2- Breast Cancer: Addressing Unmet Needs and Keys to Optimization in Clinical Practice
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Identifying Health Care Inequities in Screening, Diagnosis, and Trial Access for Breast Cancer Care: Taking Action With Evidence-Based Solutions
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Empowering Breast Cancer Patients with Non-Opioid Pain Management Innovations
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Leveraging Multidisciplinary Teams in an Evolving Treatment Landscape for Early- Stage HR+, HER2- Breast Cancer
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Coffee Talk™: Navigating the Impact of HER2/3, TROP2, and PARP from Early Stage to Advanced Breast Cancer Care
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Community Practice Connection™: Leveraging Multidisciplinary Teams in an Evolving Treatment Landscape for Early- Stage HR+, HER2- Breast Cancer
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How We Do It™: Defining HER2 Low on Your Pathology Reports to Make Informed Decisions in Breast Cancer Treatment
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Clinical Case Vignette Series™: 41st Annual Miami Breast Cancer Conference®
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Fighting Disparities and Saving Lives: An Exploration of Challenges and Solutions in Cancer Care
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24th Annual International Congress on the Future of Breast Cancer® West
July 18-19, 2025
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24th Annual International Congress on the Future of Breast Cancer® East
July 11-12, 2025
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Differentiating Adverse Events for Antibody-Drug Conjugates Across Solid Tumor Management
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Community Practice Connections™: 23rd Annual International Congress on the Future of Breast Cancer West
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School of Breast Oncology® (SOBO) Slide & Lecture Library
Joyce O’Shaughnessy, MD
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Novel Agents are Changing the Face of Metastatic TNBC
September 19th 2018Only 1 treatment option is currently available for treating patients with metastatic germline <em>BRCA</em>-mutated triple-negative breast cancer, but research into novel therapies, including PI3K/conjugates could soon result in a host of new therapies for this hard-to-treat disease.
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Promising Results Seen With Alpelisib Combo in PIK3CA+ Breast Cancer
August 24th 2018The primary endpoint for the phase III SOLAR-1 trial has been met, with improved progression-free survival seen with the combination of alpelisib and fulvestrant compared with fulvestrant alone in postmenopausal women and men with HR-positive, HER2-negative, <em>PIK3CA</em>-mutant advanced or metastatic breast cancer that had progressed after aromatase inhibitor treatment with or without a CDK4/6 inhibitor.
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Early Signs of Efficacy Seen With Mesothelin CAR T-Cell Therapy
August 17th 2018Mesothelin-targeted chimeric antigen receptor T-cell therapy has shown early evidence of efficacy in a phase I trial of patients with malignant pleural disease and mesothelioma, non–small cell lung cancer, or breast cancer. Additionally, significant responses were seen in patients who went on to receive subsequent PD-1 checkpoint inhibition treatment.
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Immunotherapy Combination in HER2-Positive Breast Cancer
August 3rd 2018Kevin Kalinsky, MD, MS, assistant professor of medicine at Columbia University, discusses the results from a trial in HER2-positive breast cancer that was presented at the 2017 San Antonio Breast Cancer Symposium. The study looked at the use of trastuzumab (Herceptin) in combination with a checkpoint inhibitor in patients that were either PD-L1-positive or negative.
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Trastuzumab Biosimilar Receives Approval in Europe for Breast and Gastric Cancers
August 2nd 2018The European Union has approved PF-05280014 (Trazimera), a biosimilar for trastuzumab (Herceptin), to treat patients with HER2 overexpressing metastatic or early breast cancer and HER2 overexpressing metastatic gastric or gastroesophageal junction adenocarcinoma.
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FDA Approves Magnetic System for Guiding Lymph Node Biopsy in Breast Cancer
July 27th 2018Magtrace and Sentimag Magnetic Localization System, which uses magnetic detection to identify sentinel lymph nodes for surgical removal in women undergoing mastectomy for breast cancer, has gained approval from the FDA.
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Sacituzumab Govitecan Granted Priority Review by FDA for TNBC
July 18th 2018A biologics license application for sacituzumab govitecan has been granted a priority review by the FDA for the treatment of patients with metastatic triple-negative breast cancer following at least 2 prior therapies for metastatic disease, Immunomedics, the manufacturer of the antibody-drug conjugate, has announced.
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Ribociclib Granted Expanded FDA Approval in Breast Cancer
July 18th 2018Upfront ribociclib (Kisqali) has been granted approval by the FDA for use in combination with an aromatase inhibitor (AI) for the treatment of pre/perimenopausal or postmenopausal women with HR-positive/HER2-negative advanced or metastatic breast cancer. Additionally, ribociclib was approved in combination with fulvestrant for postmenopausal women with HR-positive/HER2-negative advanced or metastatic breast cancer.
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