Next Few Years Will Bring Immunotherapy to the Forefront of Therapy for Urothelial Carcinoma
March 28th 2017Evan Y. Yu, MD, discusses the current treatment options for metastatic urothelial carcinoma, the unmet needs that still exist in this space, and the possibilities for the future treatment landscape.
Expert Highlights Data Supporting Moderate Hypofractionation as New Standard in Prostate Cancer
March 23rd 2017James B. Yu, MD, discusses the current data in support of using moderate hypofractionation in prostate cancer, as well as recent data showing how genomic testing can help with treatment decision making postoperatively.
Balar Discusses Current and Emerging Immunotherapy Treatments in Urothelial Carcinoma
March 23rd 2017Arjun Balar, MD, discusses the treatment considerations he makes when treating patients with urothelial carcinoma, the role of PD-L1 tumor expression and immune checkpoint inhibitors, and the potential for new immunotherapy agents in this space.
Expert Discusses Success Seen With Niraparib Maintenance Therapy for Ovarian Cancer
March 15th 2017Ursula A. Matulonis, MD, discusses results of the phase III NOVA trial showed the PARP inhibitor niraparib demonstrated an improvement in PFS versus placebo as a maintenance therapy for patients with high-grade serous ovarian cancer.
New Study Aims to Extend TTFields Beyond Grade IV Brain Cancer Domain
January 17th 2017The use of tumor treating fields as a treatment for patients with brain tumors has, thus far, largely been focused on in glioblastoma, but an upcoming trial aims to expand the use of the device to the grade III patient population, says Daniel O’Connell, MD.
Expert Discusses Impact of Prophylactic Regimen on Neratinib-Related Diarrhea in HER2+ Breast Cancer
January 5th 2017In a recent early-stage HER2-positive breast cancer trial, prophylactic treatment with the combination of loperamide and budesonide reduced the rate of grade 3 diarrhea associated with neratinib to 15%.
AeroForm Tissue Expansion Device Receives FDA Marketing Approval for Patients Following Mastectomy
December 22nd 2016The FDA has approved the marketing of AeroForm, a new system for soft tissue expansion in 2-stage breast reconstruction following mastectomy, and in the treatment of underdeveloped breasts and soft tissue deformities.
Metabolic Pathways May Provide Opportunity for Novel Therapeutic Targeting in Neuro-Oncology
December 21st 2016In an interview with <em>Targeted Oncology</em>, Howard Fine discusses the reason for renewed interested in metabolic targets, the effect it has had on treatment of gliomas, and what he sees on the horizon for neuro-oncology in this area.<br />
Expanded Committee Anticipates Watershed Year for Miami Breast Cancer Conference
December 17th 2016The 2017 Miami Breast Cancer Conference, to be held March 9 to 12 at the Fontainebleau Miami Beach, welcomes an expanded group of program chairs, and a newly established curriculum committee made up of a multidisciplinary group of breast cancer specialists.
Entrectinib Will Likely Play an Increasing Role in Treating Brain Tumors, Other Cancers, Expert Says
November 30th 2016Researchers are currently investigating the use of tropomyosin receptor kinase (TRK) inhibitor entrectinib (RXDX-101) to treat patients with relapsed or refractory solid tumors or primary tumors of the central nervous system.
New Agents, Targets Continue to Emerge in Sarcoma, Cementing Role for Immunotherapy
November 29th 2016Breelyn Wilky, MD, recently sat down <em>Targeted Oncology</em> to discuss recent findings of a trial investigating axitanib and pembrolizumab in soft tissue sarcomas, as well as the role she envisions for immunotherapy in the treatment of sarcoma.
Nancy Davidson to Head Clinical Oncology at Fred Hutch/University of Washington
October 21st 2016Nationally recognized oncologist Nancy E. Davidson, MD, has accepted the position of Executive Director of Clinical Oncology at the Fred Hutch/University of Washington (UW) Cancer Consortium in Seattle, Washington. Davidson was previously Director of the the University of Pittsburgh Cancer Institute (UPCI).
What's Next for Immunotherapy in GBM: IDO Inhibitors, Vaccines, and PD-L1 Antibody Combinations
October 18th 2016Rimas Lukas, MD, discusses the next steps in glioblastoma research, as well as the potential use of IDO inhibitors in the treatment of GBM, and recent studies showing promise in the field.
Expert on Role for Ibrutinib, Chemo, and Novel Combos in First-Line CLL
October 14th 2016Steve Coutre, MD, discusses how he determines which CLL treatment option is best for which patient, the advantage of treating patients with ibrutinib over chemoimmunotherapy, and new oral agents currently being investigated in the space.
GIST Experts Moving Toward Personalized Medicine Approach to Treatment
October 5th 2016Lori Rink, PhD, speaks about what oncologists have learned about GIST in the past 3 decades, the important role of imatinib mesylate (Gleevec) in treating the disease, and the personalized treatment approach on the horizon.
Researchers Join Forces to Accelerate Progress in Pediatric High-Grade Gliomas
September 20th 2016Goals of "Project Impact: A Campaign to Defeat Pediatric Brain Tumors" include improving clinical outcomes for pediatric brain tumor patients and informing the development of the first-ever standard of care for treating pediatric high-grade gliomas.