Expert Discusses Abemaciclib Plus Anastrazole Trial in HR+/HER2- Breast Cancer
December 21st 2016According to results presented during the 2016 San Antonio Breast Cancer Symposium, neoadjuvant combination of CDK4/6 inhibitor abemaciclib plus anastrazole may represent a novel therapeutic option for patients with hormone receptor (HR)-positive, HER2-negative early breast cancer.
Lead neoMONARCH Researcher Provides Insight on Abemaciclib Potential in HR-Positive Breast Cancer
December 11th 2016Recent promising findings with the neoadjuvant combination of the CDK4/6 inhibitor abemaciclib with anastrozole could lead to a novel therapeutic option for patients with hormone receptor (HR)–positive, HER2-negative early breast cancer.
Addressing the Challenges of Treating Non-Driver NSCLC
November 15th 2016Targeted therapies have revolutionized the treatment of patients with non–small cell lung cancer; however, not all patients harbor identifiable driver mutations. Standard treatment options among patients lacking molecular targets include chemotherapy and antiangiogenesis agents.
Anticipated METRIC Results Could Lead to First Targeted Agent Approved in TNBC
November 12th 2016Findings from a highly anticipated, randomized, phase II trial could possibly pave the path for the FDA approval of the first targeted therapy for patients with triple-negative breast cancer (TNBC), explains Linda T. Vahdat, MD.<br />
Novel ALK Inhibitor Shows Encouraging Activity in Early NSCLC Study
November 5th 2016Ensartinib (X-396), a novel small-molecule tyrosine kinase inhibitor (TKI) developed to target patients with ALK-positive non–small cell lung cancer (NSCLC), demonstrated promising clinical activity in that subset of patients who are crizotinib (Xalkori)-naïve or crizotinib-resistant.
Lau Talks Controversy Surrounding PSA Biomarker in Prostate Cancer Screening
November 2nd 2016Clayton S. Lau, MD, highlights the importance of active surveillance, the evolution of surgical techniques and radiation therapy, and the steps oncologists should take once early-stage prostate cancer progresses.
Expert Shares Latest Therapeutic Developments for Patients with HER2+ Breast Cancer
October 25th 2016In an interview with<em> Targeted Oncology</em>, Kimberly L. Blackwell, MD, discusses the latest therapeutic developments for patients with HER2-positive breast cancer while providing insight on the hurdles that still remain.