Flinn Analyzes Data from 5-Year Follow-Up of Phase III BRIGHT Trial in Frontline MCL
May 15th 2019In an interview with <em>Targeted Oncology</em>, Ian W. Flinn, MD, PhD, discussed the findings from the phase III BRIGHT trial for patients with MCL. He also highlighted the impact of BR in this patient population and other combinations under active investigation.
Lower Osimertinib Dose Shows Similar Efficacy in EGFR+ NSCLC With Leptomeningeal Metastases
May 15th 2019Myung-Ju Ahn, MD, discusses the results from the AURA LM trial and the next steps that need to be taken in order to confirm the efficacy that was seen with the lower dose. In addition, she highlights where research in the treatment landscape of advanced NSCLC is headed.
Arun Highlights Importance of Identifying BRCA1/2 Mutations in Metastatic Breast Cancer
May 14th 2019In an interview with <em>Targeted Oncology</em>, Banu Arun, MD, discussed the role of genetic testing in patients with metastatic breast cancer. She highlighted the importance of identifying various mutations, including <em>BRCA1/2 </em>mutations in light of the approval of PARP inhibitors. In addition, she spoke to how the role of genomic testing is evolving in this field with the development of new targeted agents.
Expert Highlights Ongoing Trial Evaluating Durvalumab Efficacy, Safety in Real-World Setting
May 9th 2019Nicolas Girard, MD, discussed the importance of evaluating durvalumab in a real-world setting. In addition, he highlights other questions that remain unanswered in this area, as well as the role of immunotherapy in patients with NSCLC.
Newly Established I-131 Principles Bring Multidisciplinary Collaboration to Thyroid Cancer Community
May 8th 2019R. Michael Tuttle, MD, discusses the outcomes from a 2-day interactive meeting which brought together thryoid cancer experts across 4 organizations and 8 countries to discuss the use of radioactive iodine therapy, including the development of 9 principles for the optimal management of patients.
MD Anderson Expert Highlights Ongoing Research Across Thyroid Cancer Subtypes
April 25th 2019Maria E. Cabanillas, MD, discusses some of the ongoing thyroid cancer clinical trials at The University of Texas MD Anderson Cancer Center, as well as other promising research on the horizon across all subtypes of the disease.
Coleman Highlights Benefit With Maintenance Rucaparib Across Ovarian Cancer Subgroups
April 8th 2019Analyses from the phase III ARIEL3 trial presented during the 2019 Society of Gynecologic Oncology Annual Meeting showed that rucaparib is safe and effective as a maintenance therapy across all subgroups of patients.
Updates to Ovarian Cancer Guidelines Emphasize Importance of Germline, Somatic Testing
April 5th 2019In an interview with <em>Targeted Oncology, </em>David O’Malley, MD, discussed the updates with bevacizumab and PARP inhibitors as a treatment and maintenance therapy option for patients with ovarian cancer and recurrent disease. He also discussed considerations for selecting the right agent for the right patient.
Radiation Expert Highlights Role of Radioactive Iodine in Differentiated Thyroid Cancer
March 29th 2019Radiation oncologist Jimmy J. Caudell, MD, PhD,discusses the role of radioactive iodine therapy in patients with DTC. He also highlights areas of research that may help determine the best treatment regimens and doses for select patients.
Bladder Cancer Guidelines Highlight Arrival of Immunotherapy
March 25th 2019Thomas W. Flaig, MD, discusses the latest updates to the NCCN guidelines for the treatment of patients with muscle-invasive bladder cancer. In addition, he highlights the latest approvals of checkpoint inhibitors in this patient population.
Ahead of SGO, Westin Sheds Light on Treatment Considerations for Recurrent Ovarian Cancer
March 16th 2019Ahead of the 50th Annual SGO Meeting, Shannon Westin, MD discussed the key takeaways from a case chat and highlighted some data she is looking forward to at the meeting for patients with recurrent ovarian cancer. She also highlighted other data that will play an important part in this treatment landscape and for patients with recurrent cervical cancer.
MCL Field Gaining Better Understanding of Patient Subsets to Guide Treatment
March 5th 2019Andre Goy, MD, discusses some of the recent changes that have been seen in the treatment landscape for patients with MCL and some of the ways these subsets of patients are being identified in order to find the best treatment option for an individual patient.
Reduced Palbociclib Dose Associated With Lower Rate of Neutropenia in HR+ Metastatic Breast Cancer
March 5th 2019Hope Rugo, MD, discusses results from a trial that evaluated a reduced dose of palbociclib in patients with HR+ metastatic breast cancer. She also shares details from research for a scalp cooling cap to reduce hair loss for patients with breast cancer.
Targeted Therapies Advancing Thyroid Cancer Treatment Paradigm
March 1st 2019Lori J. Wirth, MD, discusses the current treatment options for patients with advanced thyroid cancers, in addition to some of the trials that are currently enrolling at her center. She also highlights early data that have been presented for targeted therapies in advanced thyroid cancer.