Mirvetuximab Soravtansine Plus Bevacizumab Shows Promising Efficacy in Ovarian Cancer
September 17th 2018David O’Malley, MD, lead investigator of the FORWARD II trial, discusses the emerging combination of mirvetuximab soravtansine plus bevacizumab and the evolving treatment landscape in ovarian cancer.
BTK Inhibitors Will Make Significant Impact in MCL, Expert Says
September 7th 2018In an interview with <em>Targeted Oncology</em>, Simon Rule, MD, PhD, professor of Hematology at Plymouth University Medical School, United Kingdom, discusses the current treatment paradigm for MCL, as well as the potential use of BTK inhibitors for the treatment of this patient population.
Flaherty Highlights Best-In-Class Findings With BRAF/MEK Inhibitor Combo in Melanoma
September 6th 2018Keith T. Flaherty, MD, discusses results for the combination of encorafenib and binimetinib in patients with <em>BRAF</em>-mutated melanoma investigated in the COLUMBUS trial. He also highlights the potential implications and next steps.
Expert Reflects on "Incredible" Data Seen With bb2121 in Heavily Pretreated Myeloma
August 29th 2018Noopur Raje, MD, discusses the latest treatment advances in multiple myeloma, including the promising results seen with the anti-BCMA CAR T-cell therapy bb2121 in patients with relapsed/refractory disease.
Examining Immunotherapy Treatment Options in Colorectal Cancer
August 24th 2018Checkpoint inhibitors have provided practice-changing therapeutic targets for clinicians by regulating host immune response. The treatment landscape in colorectal cancer has significantly changed as a result, but more research is necessary for certain subtypes, particularly the microsatellite stable patient population.
Examining Recent Data With Niraparib, Immunotherapy in Ovarian Cancer
August 22nd 2018Ursula A. Matulonis, MD, lead author of the phase II QUADRA trial, discusses the activity and tolerability of niraparib in patients with heavily pretreated homologous recombinant deficiency-positive ovarian cancer, and other recent data in ovarian cancer.
Investigator Shares Excitement for Impressive Findings With Pembrolizumab and Bevacizumab in mRCC
August 15th 2018Treatment with pembrolizumab and bevacizumab proved to be a promising combination regimen for patients with metastatic renal cell carcinoma, according to phase Ib/II data presented at the 2018 ASCO Annual Meeting.
Despite Previous Findings, Prostate Cancer Analysis Shows Risk of Death Lower in African-Americans
August 15th 2018Susan Halabi, PhD, discusses an analysis that found that the risk of death from metastatic castration-resistant prostate cancer was nearly 20% lower in African-American men than in Caucasian men.