Barbara O'Brien, MD

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Barbara O’Brien, MD, is an associate professor of neuro-oncology at MD Anderson Cancer Center.

Articles

Advancing Trials for HER2+ Breast Cancer With Leptomeningeal Metastasis

December 1st 2024

Barbara O’Brien, MD, discusses the next steps of the phase 2 TBCRC049 study for the treatment of patients with HER2-positive breast cancer and leptomeningeal metastasis.

O’Brien on the TBCRC049 Trial in HER2+ Breast Cancer

Barbara O'Brien, MD

November 19th 2024

Barbara O’Brien, MD, discusses the background behind the phase 2 TBCRC049 study investigating the combination of tucatinib, trastuzumab, and capecitabine for the treatment of patients with HER2-positive breast cancer and leptomeningeal metastasis.

Study Shows First Evidence of Effective Systemic Therapy for HER2+ Breast Cancer With LM

Barbara O'Brien, MD

July 16th 2024

Barbara O'Brien, MD, discusses the goals and results of a study investigating tucatinib, trastuzumab, and capecitabine for the treatment of leptomeningeal metastases in patients with HER2-positive breast cancer.