Recurrent Cutaneous Squamous Cell Carcinoma
Recurrent Cutaneous Squamous Cell Carcinoma
Case: A 74-Year-Old Male With Recurrent Metastatic CSCC
November 2017
- A 74-year-old male from Florida, with history of multiple resections of CSCC on neck, back and shoulders presents with new deep lesion that exhibited perineural invasion and c/o palpable left axillary mass
- Imaging confirmed 6cm left axillary nodal conglomerate
- Patient treated with neoadjuvant cisplatin/5FU for 3 cycles
- Surgical resection of primary lesion; Lymphadenectomy revealed CSCC involvement in 12 out of 16 resected lymph nodes
May 2018
- Follow-up scans revealed early disease progression with multiple pulmonary nodules
- Patient started on carboplatin/paclitaxel for 3 cycles
November 2018
- Repeat imaging showed disease progression in pulmonary nodules and multiple lymphadenopathies; mediastinal, left and right axillary; bone metastases
- Patient started on cemiplimab for 3 cycles
February 2019
- Reimaging PET-CT revealed reduction in size and metabolic activity of right and left axillary, and mediastinal lymphadenopathies; pulmonary nodules had considerable reduction in size and were no longer substantial
Atlas Examines Tolerability of Hedgehog Pathway Inhibitors and Transition to IO in mBCC
October 16th 2024During a Case-Based Roundtable® event, Jennifer L. Atlas, MD, discussed treatment for a patient with basal cell carcinoma who reported challenging adverse events with hedgehog pathway inhibitor.
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Tawbi Discusses the Role of Brain Metastases and PD-L1 Status in Melanoma
September 11th 2024During a Case-Based Roundtable® event, Hussein A. Tawbi, MD, PhD, and participants look at benefits of nivolumab combinations for brain metastases and PD-L1 positivity in the metastatic melanoma population in the second article of a 2-part series.
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