Dr. Eytan Stein on Multiple Targets in Acute Myeloid Leukemia
Eytan Stein, MD, discusses targeting multiple mutations in patients with acute myeloid leukemia (AML).
Eytan Stein, MD, hematologist/oncologist, Memorial Sloan Kettering Cancer Center, discusses targeting multiple mutations in patients with acute myeloid leukemia (AML).
Stein says all patients with AML have a multitude of mutations that are causing their disease, and that targeting single mutations such as FLK3 and IDH may not be enough to make an impact. He adds that combining agents that, for example, target both of those mutations could very well be the future of the treatment paradigm.
First Dose of CD38-Targeting CAR T-Cell Therapy Administered in AML
January 22nd 2025The first patient with relapsed/refractory acute myeloid leukemia has received KJ-C2320, an allogeneic CAR T-cell therapy targeting CD38 and developed using the THANK-uCAR platform, in an investigator-initiated trial in China.
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Deciding on Therapy for a Patient With High-Risk Relapsed CLL
January 20th 2025During a Case-Based Roundtable® event, Nakhle Saba, MD, and participants discussed treatment for a patient with chronic lymphocytic leukemia who received 1 prior line of therapy in the first article of a 2-part series.
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Fedratinib Shows Promise in Chronic Neutrophilic Leukemia and MDS/MPN
January 20th 2025In an interview, Andrew Kuykendall, MD, discussed fedratinib’s potential as an effective option for patients with myelodysplastic syndrome/myeloproliferative neoplasms and chronic neutrophilic leukemia.
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