ELOQUENT-2 Study in Patients With Relapsed/Refractory Multiple Myeloma
Sagar Lonial, MD, professor, School of Medicine, executive vice chair, Department of Hematology & Medical Oncology, chief medical officer, Winship Cancer Institute, Emory University, discusses the ELOQUENT-2 study in patients with relapsed/refractory multiple myeloma.
The trial was based on results from early phase I/II trials that showed that elotuzumab and lenalidomide are synergistic when given together, said Lonial. There was also a better overall response rate and longer progression-free survival with the addition of elotuzumab.
Lonial says more than 300 patients were randomized to each arm, and roughly one-third of patients had high-risk disease at the time of initial presentation.
Sagar Lonial, MD, professor, School of Medicine, executive vice chair, Department of Hematology & Medical Oncology, chief medical officer, Winship Cancer Institute, Emory University, discusses the ELOQUENT-2 study in patients with relapsed/refractory multiple myeloma. This was a randomized phase III trial that evaluated the benefit of elotuzumab in combination with lenalidomide and dexamethasone versus lenalidomide and dexamethasone without elotuzumab.
Gasparetto Explains Rationale for Quadruplet Front Line in Transplant-Ineligible Myeloma
February 22nd 2025In a Community Case Forum in partnership with the North Carolina Oncology Association, Cristina Gasparetto, MD, discussed the CEPHEUS, IMROZ, and BENEFIT trials of treatment for transplant-ineligible newly diagnosed multiple myeloma.
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