ELOQUENT-2 Study in Patients With Relapsed/Refractory Multiple Myeloma
Sagar Lonial, MD, professor, School of Medicine, executive vice chair, Department of Hematology & Medical Oncology, chief medical officer, Winship Cancer Institute, Emory University, discusses the ELOQUENT-2 study in patients with relapsed/refractory multiple myeloma.
The trial was based on results from early phase I/II trials that showed that elotuzumab and lenalidomide are synergistic when given together, said Lonial. There was also a better overall response rate and longer progression-free survival with the addition of elotuzumab.
Lonial says more than 300 patients were randomized to each arm, and roughly one-third of patients had high-risk disease at the time of initial presentation.
Sagar Lonial, MD, professor, School of Medicine, executive vice chair, Department of Hematology & Medical Oncology, chief medical officer, Winship Cancer Institute, Emory University, discusses the ELOQUENT-2 study in patients with relapsed/refractory multiple myeloma. This was a randomized phase III trial that evaluated the benefit of elotuzumab in combination with lenalidomide and dexamethasone versus lenalidomide and dexamethasone without elotuzumab.
FDA Greenlights Treosulfan/Fludarabine Combo for AlloHSCT in AML and MDS
January 24th 2025The combination of treosulfan and fludarabine as a preparative regimen for allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia or myelodysplastic syndromes has been approved by the FDA.
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