Dr. Roy Herbst on Antibodies Used Against EGFR Alongside Chemotherapy
Dr. Roy S. Herbst discusses a 5 year study focusing on the use of antibodies against EGFR alongside chemotherapy treatments.
Roy S. Herbst, MD, PhD, chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven, discusses a 5 year study focusing on the use of antibodies against EGFR alongside chemotherapy treatments.
Herbst says that the approach differs from the use of small molecules and was most effective in patients with an increased copy number of the EGFR gene, specifically those with more than four copies of the gene. He says the extra genes discovered in patients were through the use of fluorescent in situ hybridization (FISH).
Enasidenib Shows Promise as Post-Transplant Maintenance in IDH2-Mutated AML
January 7th 2025Amandeep Salhotra, MD, discussed the background and findings from a pilot trial evaluating enasidenib as post-hematopoietic stem cell transplant maintenance therapy for IDH2-mutated acute myeloid leukemia treatment.
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Could Triapine With Lutetium 177 Dotatate Improve Outcomes for Neuroendocrine Tumors?
December 30th 2024Aman Chauhan, MD, highlights an ongoing phase 2 trial exploring the combination of triapine, a radiation sensitizer, with lutetium 177 dotatate for treating well-differentiated somatostatin receptor–-positive neuroendocrine tumors.
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