Pacritinib Shows Tolerable Safety Profile for Thrombocytopenic Myelofibrosis
Srdan Verstovsek, MD, PhD, discusses the tolerability of pacritinib for patients with myelofibrosis.
Watch
Chronic GVHD: Prognoses and Future Directions in Care
Closing out their discussion on graft-versus-host disease, participants reflect on patient prognoses and the future directions of care.
Scenario 2: Treatment-Induced Damage in Chronic GVHD
A brief discussion on the risk of treatment-induced damage when managing patients with chronic graft-versus-host disease.
Scenario 2: Selecting Therapy for Steroid-Refractory GVHD
Having reviewed approved treatment options for steroid-refractory, chronic GVHD, experts discuss how they would address this patient scenario.
Scenario 2: Belumosudil and Axatilimab as Treatment Options in cGVHD
Considerations for belumosudil and axatilimab as treatment options for steroid-refractory chronic graft-versus-host disease.
Scenario 2: Ibrutinib and Ruxolitinib as Treatment Options in cGVHD
A review of treatment options approved for steroid-refractory chronic graft-versus-host disease starting with ibrutinib and ruxolitinib.
Scenario 2: Identifying Chronic GVHD and Risk Status
Shared insight on how to distinguish chronic GVHD from acute GVHD, as well as utilize appropriate methods to risk stratify disease.
Scenario 2: Challenges in Early Intervention for Chronic GVHD
Shifting their focus to chronic graft-versus-host disease, experts review a patient scenario and discuss the challenges in early intervention.
Improving Outcomes for Patients With Appendiceal Cancer
Andreana Holowatyj discusses the key takeaway for community oncologists about early-onset appendiceal cancer.
EGFR Tyrosine Kinase Inhibitors and SCLC Transformation
Ravi Salgia, MD, explains how treatment with a tyrosine kinase inhibitor in patients with non–small cell lung cancer can lead to disease transformation.
GVHD Prophylaxis Expands Graft Source Options for MDS
Ronald L. Paquette, MD, discusses the selection of graft source for bone marrow and stem cell transplants in patients with myelodysplastic syndrome.
Choosing BTK Inhibitors Versus Venetoclax as First-Line CLL Therapy
Nilanjan Ghosh, MD, PhD, discusses when a Bruton’s tyrosine kinase inhibitor would be preferred over a BCL-2 inhibitor as first-line therapy for patients with chronic lymphocytic leukemia.
Scenario 1: Optimizing Management of Acute GVHD
Experts review the prognosis of a patient with acute graft-versus-host disease and identify ways to optimize their treatment strategies.
Scenario 1: Selecting Therapy for Acute Graft-Versus-Host Disease
A panel of experts discuss systemic therapy to manage a patient with acute graft-versus-host disease.
Scenario 1: Acute GVHD Symptomology and Patient Education
Centering discussion on a patient scenario of acute graft-versus-host disease, participants discuss nuance in disease symptomology and patient education.
Retrospective Study Shows Adoption of Immunotherapy in ES-SCLC
Eric Nadler, MD, MPP, discusses the design and goals of a retrospective study of real-world adoption of atezolizumab immunotherapy in extensive-stage small cell lung cancer.
Key Questions for Improving Outcomes With Pembrolizumab in PD-L1+ TNBC
Lee Schwartzberg, MD, discusses important questions that have been raised due to the positive results of pembrolizumab immunotherapy for patients with triple-negative breast cancer.
Virtual Tumor Board®: An Overview on Graft-Versus-Host Disease and Prophylaxis
Expert perspectives on the nature and occurrence of graft-versus-host disease alongside available prophylactic regimens.
SEQUOIA Trial Evaluates Zanubrutinib in Patients With CLL
Jennifer Brown, MD, PhD discusses the purpose of the SEQUOIA trial in patients with treatment-naïve chronic lymphocytic leukemia.
Glofitamab Shows Efficacy in BTK Inhibitor-Refractory MCL
Tycel Phillips, MD, discusses the potential use of glofitamab as therapy for patients with relapsed/refractory mantle cell lymphoma.
Use of Olaparib in Patients With BRCA+/HER2- High-Risk Early Breast Cancer
Charles Geyer, MD, discusses olaparib for the treatment of patients with BRCA-positive, HER2-negative high-risk early breast cancer as evaluated in the OlympiA study.
Targeted Agents Show Efficacy in KRAS-Mutated NSCLC
Lyudmila Bazhenova, MD, discusses targeted therapies for patients with KRAS-mutated non–small cell lung cancer.
Steroid-Refractory Chronic GVHD: Unmet Needs and Future Directions
Closing out his discussion, Yi-Bin Chen, MD, talks about unmet needs, ongoing clinical trials, emerging treatment options for patients with steroid-refractory chronic GVHD.
Reflections on the Case and Risk Management for Chronic GVHD
Yi-Bin Chen, MD, reflects on the patient case and outlines strategies for educating and managing patients at risk of developing chronic GVHD.
Ruxolitinib Safety in Steroid-Refractory Chronic GVHD
A brief overview of safety and adverse events in the REACH3 trial of ruxolitinib in patients with steroid-refractory chronic GVHD.
Ruxolitinib Efficacy in Steroid-Refractory Chronic GVHD
A discussion of data from the REACH3 trial and real-world data on the efficacy of ruxolitinib in patients with steroid-refractory chronic GVHD.
Treatment Options for Steroid-Refractory Chronic GVHD
Yi-Bin Chen, MD, discusses available treatment options for patients with steroid-refractory chronic GVHD.
Early Diagnosis of Chronic GVHD and Tools for Severity Assessment
Insight on early diagnosis of chronic GVHD and the tools clinicians use to assess GVHD severity.
Symptoms and Manifestations of Chronic GVHD
A comprehensive overview of the symptoms of and organs involved in chronic GVHD.
Evolving Treatment Landscape for Patients With Renal Cell Carcinoma
Nicholas J. Vogelzang, MD, discusses some of the approvals and different regimens seen in today’s renal cell carcinoma treatment landscape.