Patient Case 2: mNSCLC with an EGFR Exon 20 Insertion
Dr Ana Velázquez Mañana introduces a second patient case, a 59-year-old Black man diagnosed with mNSCLC and an EGFR exon 20 insertion, and outlines first-line treatment selection for the patient.
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A 67-Year-Old Man with Polycythemia Vera
Prithviraj Bose, MD introduces a polycythemia vera (PV) patient case featuring a 67-year-old man presenting with frequent headaches and dizziness.
Overcoming Disparities in Biomarker Testing Use for mNSCLC
Expert panelists react to the presented data on racial and socioeconomic disparities in biomarker testing for patients with mNSCLC, and align on ways to address and overcome these disparities.
NSCLC: Selecting a Frontline ALK-Targeted TKI Therapy
A panel of experts considers which factors best inform selection of first-line ALK TKI therapy in patients with non–small cell lung cancer.
Expert Perspectives on Molecular Testing in Non–Small Cell Lung Cancer
Comprehensive discussion on molecular testing strategies utilized in non–small cell lung cancer to help inform treatment decisions.
Soiffer Discusses Relapse After Transplant
Robert J. Soiffer, MD, discusses the role of transplantation and relapse after transplant for patients with cancer.
The Future of CAR T-Cell Therapy for Acute Lymphoblastic Leukemia
Nitin Jain, MD, discusses future improvements he anticipates for autologous and allogeneic chimeric antigen receptor T-cell therapies for B-cell acute lymphoblastic leukemia and other hematologic malignancies.
Discussing the Reclassification of NIFTP
Yuri E. Nikiforov, MD, PhD, discusses the reclassification of noninvasive follicular thyroid neoplasm with papillary-like nuclear features, which has significantly influenced the thyroid cancer space.
Frontline Ibrutinib/Venetoclax Generates Prolonged uMRD Data in CLL
Carolyn Owen, MD, discusses data from the phase 3 GLOW study which were presented at the 10th Annual Meeting of the Society of Hematologic Oncology.
Unmet Needs in R/R MM and Clinical Practice Pearls
Closing their discussion, the panel highlights unmet needs in the management of relapsed/refractory multiple myeloma and shares clinical pearls for community physicians.
Case 3: Sequencing BCMA-Directed Therapies for R/R MM
Krina Patel, MD, MSc, presents the case of a 65-year-old woman with relapsed/refractory multiple myeloma, and the panel discusses the optimal sequencing of her treatment regimens.
Clinical Insights on the Future of GVHD Treatment
Closing out his discussion on chronic graft-vs-host disease, Yi-Bin Chen, MD, looks to the future of GVHD treatment.
Second-Line Approaches to Treating GVHD
Yi-Bin-Chen, MD, discusses the effect of GVHD recurrence and multiple-organ involvement on treatment decisions.
Treatments for Steroid-Refractory Chronic GVHD
A summary of the systemic treatment options available for steroid-refractory chronic GVHD.
Therapy Options for Patients with Chronic GVHD
A comprehensive overview of the various treatment options for chronic graft-vs-host disease.
Overview of GVHD Types and Symptoms
Yi-Bin Chen, MD, describes acute and chronic GVHD, and details the typical symptoms and presentations.
Acknowledging Insurance-Mediated Disparities in Gynecologic Cancers
Anna Jo Bodurtha Smith, MD, discusses background on her research regarding insurance-mediated disparities in gynecologic oncology.
Discussing the Role of Tivozanib in the Third-Line of RCC Treatment
With updated data for the usefulness of tivozanib, patients with recurrent clear cell renal carcinoma have an effective option for treatment in a treatment landscape previously without many treatment options.
Interesting Research in the Endometrial Cancer Space
Casey M. Cosgrove, MD, discusses research exploring precision medicine concepts for endometrial cancer treatment.
Opportunities for Individualizing Endometrial Cancer Treatment
Casey M. Cosgrove, MD, discusses biomarker-guided treatment for endometrial cancer.
An Introduction to Three Real-World Analyses of Biomarker Testing Patterns in mNSCLC
Dr Jason Porter introduces three recent retrospective observational studies on use of biomarker testing in mNSCLC, which identified racial and socioeconomic disparities in testing patterns.
Challenges of Using Biomarker Testing in mNSCLC
Panelists continue their dialogue on common challenges and barriers to use of biomarker testing in NSCLC, and share potential strategies to optimize use of testing.
Studies of CAR T Cells for B-Cell Malignancies
Lori Leslie, MD, discusses ongoing clinical trials that are exploring chimeric antigen receptor T-cell therapy for the treatment of B-cell malignancies.
Transplant Conditioning Regimens and GVHD Prophylaxis
An expert on graft-vs-host disease provides an overview of GVHD prophylaxis and conditioning regimens prior to transplant.
Patient Profile: A 48-Year-Old Man with Chronic GVHD
Yi-Bin Chen, MD, an expert clinician and researcher, reviews a case study of a patient with GVHD and offers his initial impressions.
Finley Highlights His Hopes for Future SCLC Treatment Options
Gene G. Finley, MD, discusses some of the treatment options that have been used in the small cell lung cancer space, including intensive chemotherapies and targeted agents.
Methods and Design of the MYLUNG Consortium for mNSCLC
Nicholas J. Robert, MD, discusses the poster on the MYLUNG Consortium that he presented at the 2022 American Society of Clinical Oncology Annual Meeting.
Case 1: Frontline Treatment of ALK+ NSCLC With Brain Metastases
Shared insight on a patient case of ALK+ non–small cell lung cancer with CNS metastasis and the role of brain MRIs in clinical practice.
Unmet Needs in the Renal Cell Carcinoma Treatment Landscape
Chandler Park, MD shares clinical insights regarding care for patients with renal cell carcinoma, touching on treatment selection and managing adverse effects.
Clinical Insights: Ongoing Trials in the Renal Cell Carcinoma Landscape
Thoughtful discussion of ongoing clinical trials in the renal cell carcinoma landscape, with a particular focus on their eventual clinical implications.