Garje Assesses Sarcomatoid vs Classic Urothelial Carcinoma
Rohan Garje, MD, explains some of the differences between the sarcomatoid and classic carcinoma of the bladder.
Watch
The REACH3 Clinical Trial of Ruxolitinib in Chronic GVHD
Yi-Bin Chen reviews data from the REACH3 trial of ruxolitinib in patients with chronic steroid-refractory graft versus host disease.
The iNTEGRATE Trial: Ibrutinib With Prednisone as First-Line Therapy for cGVHD
The panel discusses the iNTERGRATE trial of ibrutinib in combination with prednisone as frontline therapy for chronic GVHD.
Choosing Which Patients Should Receive Adjuvant Therapy for RCC
Eric A. Singer, MD, MS, discusses which patients he believes would benefit most from adjuvant therapy for high-risk renal cell carcinoma.
Evolving Treatment Landscape in Advanced Renal Cell Carcinoma
Concluding the discussion, Dr Rana McKay discusses the current state of advanced RCC, potential breakthroughs, and best practices for optimal patient outcomes.
Clinical Considerations and Treatment Sequencing for Patients with Advanced RCC
Rana McKay, MD, provides insights into decision-making strategies and consideration for treatment sequencing in advanced RCC.
Triplet Regimens for First-Line Advanced Renal Cell Carcinoma
Discussion on triplet therapy regimens in advanced RCC and how progressing therapeutic studies can impact its future use.
Lin Reviews Data on Cilta-Cel in Multiple Myeloma
Yi Lin MD, PhD explains how results from CARTITUDE-1 impact the treatment landscape for relapsed or refractory multiple myeloma.
CheckMate 9ER: Quality of Life Data and Treatment Implications in Advanced RCC
Expert perspective on CheckMate 9ER quality of life data and treatment implications for patients with advanced RCC.
CheckMate 9ER Trial Updates
Centering discussion on the CheckMate 9ER trial, Dr. McKay shares perspective of recent follow-up data of nivolumab + cabozantinib in frontline advanced RCC.
Limitations in Treatment of Metastatic Renal Cell Carcinoma
Reflection on biomarkers, treatment resistance, and other unmet needs in 1L treatment of advanced RCC by Rana R. McKay, MD.
First-Line Treatment Strategies in Renal Cell Carcinoma
Dr Rana McKay provides insight on preferred therapeutic options for first-line treatment of RCC and how patient risk stratification influences decision making.
Overview of Advanced RCC and Diagnosis
Rana R. McKay, MD, reflects on the landscape of advanced RCC, discusses histology, subsets of kidney cancer, and IMDC criteria for prognostic stratification.
Recent Progress and Unmet Needs in NSCLC
Dr. Florez and Dr. Sabari delve into areas of progress, unmet needs, and future research in NSCLC, encompassing novel biomarkers and targeted therapies such as CEACAM5.
HR+/HER2- Metastatic Breast Cancer: Impact of ESR1 Mutation on Treatment
Before closing out their module on ESR1 mutation, panelists identify its impact on treatment options for patients diagnosed with HR+/HER2- metastatic breast cancer.
Optimal ESR1 Testing Strategies in HR+/HER2- Metastatic Breast Cancer
In the context of ESR1 mutation in HR+/HER2- metastatic breast cancer, key opinion leaders consider ideal testing modalities and timing to improve patient outcomes.
Important Biomarkers for Cervical and Ovarian Cancers
John Diaz, discusses key targets for cervical cancer and ovarian cancer.
Studies Supporting the Use of PD-L1 Therapy Plus Chemo in ES-SCLC
Federico Albrecht, MD, comments on clinical trials supporting the use of PD-L1 inhibitor therapy in combination with standard chemotherapy for the treatment of patients with extensive-stage small cell lung cancer.
Targeting PIK3CA Mutations in Breast Cancer
Andreas Varkaris, MD, PhD, discusses PIK3CA mutations in breast cancer and the novel therapies being developed to treat these tumors.
AI-Derived Biomarker Predicts Benefit of Long-Term ADT in Prostate Cancer
Andrew J. Armstrong, MD, ScM, discusses the methods behind a study that established a digital pathology biomarker for the benefit of androgen deprivation therapy in localized high-risk prostate cancer.
Next Steps for Orca-Q in Patients Undergoing Haplo HSCT
Samer A. Srour, MD, MS, discusses what challenges need to be faced when moving forward with the phase 1 trial of Orca-Q in patients undergoing haploidentical allogeneic hematopoietic stem cell transplantation.
Future Perspectives and Unmet Needs in the Treatment of Ovarian Cancer
Chad A. Hamilton, MD, offers closing thoughts on the future outlook and unmet needs in the ovarian cancer treatment landscape.
Recent Data Updates from PRIMA and PAOLA-1 Trials in Ovarian Cancer
Key takeaways from recent data updates from the PRIMA and PAOLA-1 trials investigating PARP inhibitors in ovarian cancer.
Ovarian Cancer: Strategies for Managing GI Toxicities and Fatigue from PARP Inhibitors
Chad A. Hamilton, MD, shares strategies for managing gastrointestinal toxicities and fatigue for patients receiving PARP inhibitors for the treatment of ovarian cancer.
Adverse Events from PARP Inhibitors in Ovarian Cancer
Clinical insights on adverse effects seen with PARP inhibitors in the treatment of patients with ovarian cancer.
Considerations for Initiating Maintenance Therapy in Ovarian Cancer
An overview of factors that influence the initiation of maintenance therapy for patients with ovarian cancer.
Informing Ovarian Cancer Treatment Approach With Clinical Trial Data
Chad A. Hamilton, MD, discusses how clinical trial data inform treatment selection for patients with ovarian cancer.
Maintenance Therapy Landscape for Frontline Ovarian Cancer
A comprehensive overview of the maintenance therapy landscape in ovarian cancer, with a focus on clinical trials investigating bevacizumab, olaparib, and niraparib.
Overview of Guideline Recommendations for Molecular Testing in Ovarian Cancer
An expert gynecologic oncologist reviews guideline recommendations for molecular testing in ovarian cancer and shares his testing practices.
Patient Profile: A 49-Year-Old Woman with BRCA Wild-Type Ovarian Cancer
Chad A. Hamilton, MD, presents the case of a 49-year-old woman with BRCA wild-type ovarian cancer and offers his initial impressions.