LDK378 in ALK+ Crizotinib-Resistant NSCLC Patients
Alice T. Shaw, MD, PhD, discusses the results of a trial looking at LDK378 for patients with ALK+ crizotinib-resistant non-small cell lung cancer.
Watch
Treating Breast Cancer With Anthracyclines and Trastuzumab
Debu Tripathy, MD, from the Norris Comprehensive Cancer Center, discusses the treatment of breast cancer with anthracyclines and trastuzumab.
Patient Considerations Following Treatment With Radium-223
Neal D. Shore, MD, FACS, discusses patient considerations following treatment with radium-223 for bone metastases from prostate cancer.
Targeting the MAGE-A3 Protein in Lung Cancer
Silvia Novello, MD, PhD, from the University of Turin, Italy, gives an overview of immunotherapy and the targeting of the MAGE-A3 protein in lung cancer.
Cervical Cancer Screening in Low-Resource Countries
Electra D. Paskett, PhD, Professor, College of Medicine, The Ohio State University, discusses screening for cervical cancer.
Trials Show How Nivolumab works in Melanoma
Lynn M. Schuchter, MD, describes two trials presented at the 2013 ASCO Meeting looking at nivolumab in patients with melanoma.
Targeting the Androgen Receptor in Breast Cancer
Suzanne A. W. Fuqua, PhD, professor of medicine at Baylor College of Medicine, discusses targeting the androgen receptor in breast cancer.
The Mechanism of Action of Olaparib
Jane Robertson, MD, Global Product Vice President at AstraZeneca, describes the mechanism of action of the PARP inhibitor olaparib.
How T-rapa Cells Work
Daniel H. Fowler, MD, senior investigator, Center for Cancer Research, National Cancer Institute, describes how T-rapa cells work.
ATM, CHEK2, and PTEN Genes in Breast Cancer
Jane E. Churpek, MD, medical oncologist, hematologist, The University of Chicago, discusses the ATM, CHEK2, and PTEN genes in breast cancer.
Recent Findings on Molecular Genotyping in Lung Cancer
Giorgio V. Scagliotti, MD, PhD, from the University of Turin, discusses recent advances in the molecular genotyping of patients with lung cancer.
Pathway Changes in Breast Cancer
Hope S. Rugo, MD, from the University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, discusses pathway changes in breast cancer.
Administering the G-200 Vaccine
Andrew T. Parsa MD, PhD, from the University of California, San Francisco, describes the administration of the prophage G-200 for recurrent glioblastoma multiforme.
The Next Steps for Pertuzumab in Breast Cancer
Sandra Swain, MD, medical director of the Washington Cancer Institute at MedStar Washington Hospital Center, gives an overview of the next steps for pertuzumab in breast cancer.
Crizotinib in ROS1 Rearranged NSCLC
D. Ross Camidge, MD, PhD, discusses the potential to utilize crizotinib as a treatment for patients with advanced non-small cell lung cancer who harbor a ROS1 gene rearrange
The Design of a Chimeric Antigen Receptor
Cameron J. Turtle, MD, PhD, from the Fred Hutchinson Cancer Research Center, discusses the design of a chimeric antigen receptor (CAR).
The Clinical Utility of Ki67 in Breast Cancer
Torsten O. Nielsen, MD, PhD, FRCPC, professor, pathology, University of British Columbia, discusses Ki67 in breast cancer.
Treating ER+ Breast Cancer Patients With Antiestrogens
Richard Finn, MD, from UCLA, discusses the treatment of patients with estrogen receptor-positive (ER+) breast cancer with antiestrogens.
How PD-1 and PD-L1 Act in Various Cancers
Antoni Ribas, MD, PhD, the director of the Tumor Immunology Program Area at UCLA's Jonsson Comprehensive Cancer Center, discusses PD-1 and PD-L1 in various cancers.
T-VEC in Melanoma
Robert Andtbacka, MD, from the University of Utah School of Medicine and Huntsman Cancer Institute, discusses a trial analyzing talimogene laherparepvec (T-VEC) in melanoma.
Cyclin-Dependent Kinases and the Treatment of Cancer
Richard Finn, MD, from the Jonsson Comprehensive Cancer Center, UCLA, describes the development of cyclin-dependent kinases (CDKs) for the treatment of cancer.
Using the Immune System to Fight Cancer
Andre Goy, MD, from John Theurer Cancer Center, discusses recent research into fighting cancer with the immune system.
Hsp90 Inhibition With Ganetespib as a Lung Cancer Treatment
Suresh S. Ramalingam, MD, from the Winship Cancer Institute, discusses the investigation of the heat shock protein 90 inhibitor ganetespib as a treatment for patients with advanced lung cancer.
Repurposing Drugs to Treat Thyroid Cancer
Marcia Brose, MD, PhD, from the University of Pennsylvania, on repurposing drugs to treat thyroid cancer.
The Next Steps for Bevacizumab in Recurrent Cervical Cancer
Krishnansu S. Tewari, MD, from the University of California, Irvine, comments on the next steps for bevacizumab for recurrent cervical cancer.
ASCO's CancerLinQ Program
Clifford A. Hudis, MD, describes ASCO's CancerLinQ program, which is a direct response to the Insitute of Medicine's call for rapid learning systems.
The Design of a Trial Analyzing Selumetinib in Advanced Uveal Melanoma
Richard D. Carvajal, MD, describes the design of a phase II study of selumetinib versus temozolomide in gnaq/Gna11 mutant uveal melanoma.
Personalizing Treatment of Early-Stage Breast Cancer
Emiel J. Rutgers, MD, from the Netherlands Cancer Institute, describes the personalization of treatment for patients with early-stage breast cancer.
Using the BROCA Genetic Assay to Treat Breast Cancer
Jane E. Churpek, MD, describes the BROCA genetic assay, uses targeted genomic capture and next-generation sequencing to analyze a panel of 42 genes.
The Changing Outlook for Immunotherapies in Cancer Treatment
Howard L. Kaufman, MD, Rush University Medical Center, comments on the changing outlook for immunotherapies.