Improving Patient Outcomes With Ruxolitinib in Advanced Myelofibrosis
December 16th 2020Srdan Verstovsek, MD, PhD, discusses how research and future clinical trials can better determine the benefit of ruxolitinib as treatment of patients with myelofibrosis, which is often measured in improvements in the quality of life and spleen reductions.
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Ibrutinib Plus Rituximab Data Surprising in Waldenstrom’s Macroglobulinemia
December 15th 2020Christian Buske, MD, discusses surprising findings from the 5-Year follow-up of a randomized phase 3 trial in patients with Waldenström’s macroglobulinemia receiving of ibrutinib plus rituximab or placebo plus rituximab.
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REACH3 Study Demonstrates Promising Objective Responses in Chronic GVHD
December 8th 2020Robert Zeiser, MD, discusses the findings from the phase 3 REACH3 clinical trial of ruxolitinib as treatment of patients with chronic graft-versus-host disease with an inadequate response to corticosteroids.
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Pooled Analysis Supports Use of Acalabrutinib in Patients With Chronic Lymphocytic Leukemia
December 7th 2020Jennifer R. Brown, MD, PhD, discusses the implications of the findings from a pooled analysis of cardiovascular events from studies of the next-generation BTK inhibitor acalabrutinib monotherapy as treatment of patients with chronic lymphocytic leukemia.
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