Case Overview: 82-Year-Old Man With Metastatic CRPC
Matthew R. Smith, MD, PhD, presents the case of a 82-year-old man with metastatic castration-resistant prostate cancer (mCRPC) and shares his initial impressions.
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Case 3: Keynote-564 Discussion and Adjuvant Treatment in mRCC
The expert panel discusses trials underway in the adjuvant setting and the role of adjuvant therapy in patients with RCC.
Case 3: mRCC Keynote-564 Study
Bradley McGregor, MD, reviews data from the Keynote-564 study on the use of immunotherapy in the adjuvant setting.
Case 3: Multidisciplinary Team Engagement in RCC
The expert panel discusses the role of multidisciplinary teams in treatment of patients with RCC.
Case 3: A New Horizon in Adjuvant Therapy for RCC
Bradley McGregor, MD, reviews the case of a 62-year-old man with mRCC and the use of adjuvant therapy for RCC.
Case 2: TIVO-3 Study in mRCC
Dr Eric Jonasch and the panel discuss TIVO-3 trial data and use of tivozanib and HIF3α inhibitors in mRCC.
Case 2: Adverse-Event Management in Favorable-Risk RCC
RCC experts discuss dose modifications and management of adverse events in patients with favorable-risk mRCC.
Case 2: Second-Line Treatments in Favorable-Risk mRCC
Eric Jonasch, MD, and the panel discuss NCCN Guidelines’ preferred second-line treatment options in mRCC.
Case 2: Favorable-Risk First-Line Treatments in mRCC
The expert panel and Dr Eric Jonasch discuss data on first-line immunochemotherapy combinations for favorable-risk mRCC.
Case 2: Metastatic RCC, Favorable Risk
Eric Jonasch, MD, discusses a 62-year-old man with favorable-risk metastatic RCC and goals and treatment options for such a patient.
Risk Assessments Can Improve Tailored Treatment for Multiple Myeloma
Shaji Kumar, MD, discusses how risk assessments and new drug combinations could influence treatment of patients with newly diagnosed multiple myeloma.
Goals for TACE and Immunotherapy Trial in Intermediate-Stage HCC
Arndt Vogel, MD, discusses the goals of the IMMUTACE study investigating the efficacy of transarterial chemoembolization with nivolumab in patients with intermediate-stage hepatocellular carcinoma.
Case 1: Patient Management in RCC
Renal cell carcinoma panel discusses factors impacting first-line treatment selection and patient monitoring and adverse-event management in patients with intermediate- and poor-risk mRCC.
Case 1: CheckMate 9ER mRCC Trial
Tom Hutson, DO, PharmD, discusses efficacy and data from CheckMate 9ER, a phase 3 study, and considerations in selecting this regimen.
Case 1: Practical Considerations in mRCC
The expert panel discusses practical considerations when choosing first-line treatment in mRCC in light of CLEAR trial data.
Case 1: CLEAR Trial in mRCC
Tom Hutson, DO, PharmD, reviews data from phase 3 CLEAR trial that evaluates efficacy and safety of frontline lenvatinib and pembrolizumab or everolimus or sunitinib.
Case 1: Intermediate- and Poor Risk First-Line mRCC Treatments
Renal cell carcinoma experts discuss key efficacy data for first-line immunotherapy combinations in intermediate- and poor-risk patients with mRCC.
Case 1: Systemic Therapy Options in RCC
The expert panel discusses systemic therapy options recommended in NCCN Guidelines for patient with intermediate- and poor-risk mRCC.
Metastatic RCC Survival Approaching 5 Years
James Brugarolas, MD, PhD, discusses updated survival data in patients with metastatic renal cell carcinoma.
Potential Benefits of Lenvatinib in Renal Cell Carcinoma
Naomi B. Haas, MD, medical oncologist, discusses the potential benefits of lenvatinib for the treatment of renal cell carcinoma.
Role of Ruxolitinib in GVHD Treatment
Drs Michael Bishop and John DiPersio comment on clinical implications for the use of ruxolitinib in chronic GVHD and share insights on future directions for GVHD.
Practical Considerations for the Treatment of GVHD
Expert hematologist/oncologists consider combination therapy with ROCK and JAK inhibitors for the treatment of chronic GVHD as well as the use of ibrutinib for disease management.
Implications of the EPOCH Trial in Clinical Practice
Mary F. Mulcahy discusses the potential implications of the EPOCH trial in clinical practice.
DLBCL: Approaches for Monitoring Frontline Treatment Response
Debates regarding the proper timing for repeat scans, interval CT testing, and surveillance imaging on patients with diffuse large B-cell lymphoma following frontline therapy.
The EPOCH Trial: Efficacy and Safety
Dr Mary Mulcahy, a key opinion leader, describes the efficacy and safety outcomes of the EPOCH clinical trial.
DLBCL Risk Status and Frontline Treatment Decisions
The differences between frontline treatment strategies for early stage vs double- or triple-hit diffuse large B-cell lymphoma.
The EPOCH Trial: Rationale and Design
Dr Mary Mulcahy explains the rationale and study design of the phase III EPOCH clinical trial.
JAK Inhibitors: Managing Cytopenias in Chronic GVHD
Michael Bishop, MD, and John DiPersio, MD, PhD, discuss pulmonary complications associated with chronic GVHD and the management of cytopenias in patients treated with JAK inhibitors.
Radioembolization in Colorectal Cancer with Liver Metastasis
Dr Mary Mulcahy, an expert oncologist, details how radioembolization is involved in the treatment of colorectal cancer with liver metastasis.
Treatment Options for Newly Diagnosed Follicular Lymphoma
Mark J. Roschewski, MD, discusses standard of care options for the treatment of follicular lymphoma.