Treating DTC With Lenvatinib
Dr Brose elaborates on treating patients with DTC with lenvatinib, including starting dosage and toxicities/adverse events.
Study 211 and HRQoL: Lenvatinib and RR-DTC
A medical professional discusses Study 211 data and HRQoL analyses for patients with DTC on lenvatinib.
Lenvatinib and Age
An expert explains the impact of patient age when taking lenvatinib for treatment.
Frontline Treatment Options in RR-DTC
Dr Brose reviews frontline treatment options for radioiodine-refractory differentiated thyroid cancer (RR-DTC).
Patient Case 1: A 70-Year-Old Woman with Differentiated Thyroid Cancer
Marcia S. Brose, MD, PhD, introduces our first patient case, a 70-year-old woman with differentiated thyroid cancer (DTC).
ER+ Early Breast Cancer Future Directions and A Note on Ki-67 Analyses
Lowell Hart, MD, FACP, discusses what he’d like to see in the future for the treatment of ER+ breast cancer and includes a note concerning Ki-67 analyses.
Case Patient Prognosis
Dr Hart explains his prognosis for our case patient.
Common Adverse Events With CDK4/6 Inhibitors
Lowell Hart, MD, FACP, lists the different types of adverse events that are common when CDK4/6 inhibitors are used in both the adjuvant and advanced cancer setting.
CDK4/6 Inhibitor Breast Cancer Clinical Trials
Dr Hart delves into the CDK4/6 inhibitor clinical trials for breast cancer, some that he’s even participated in.
Adjuvant Therapy Options for HR+ Breast Cancer
Dr Hart explains the different adjuvant therapy options for patients with HR+ breast cancer.
Introduction: A 54-Year-Old Woman With ER+/PR+ Breast Cancer
Lowell Hart, MD, FACP, introduces our patient case, a 54-year-old woman with ER+/PR+ breast cancer, and discusses his strategy and the risk of recurrence for the disease.
Using Abiraterone as a Front-Line Therapy for mCSPC and PEACE-1 Trial Details
Dan Petrylak, MD, discusses the pros and cons of using abiraterone as a front-line therapy for mCSPC and provides details of the PEACE-1 study.
Case 2 Introduction: A 62-Year-Old Man With mCSPC and Front-Line Approach
Dr Petrylak presents our second case, a 62-year-old man with mCSPC.
Unmet Needs and Key Takeaways When Treating mCSPC
An expert explains the unmet needs in the mCSPC landscape, as well as key takeaways if you are treating patients with this disease.
mCSPC and the TITAN Study
Dr Petrylak recalls the study design and results of the TITAN study.
Case 1: An 80-Year-Old Man With mCSPC
Dan Petrylak, MD, presents our first case for discussion, an 80-year-old man with metastatic castration-sensitive prostate cancer (mCSPC). Front-line therapy options and monitoring for mCSPC are also mentioned.
Future Developments With BTKi
Mazyar Shadman, MD, MPH, and Jonathon Cohen, MD, MS, discuss possible future developments with BTKi as therapy options in B-cell lymphomas.
Third Generation BTKi and Unmet Needs
Drs Shadman and Cohen introduce new data concerning a third-generation BTK inhibitor, pirtobrutinib, and discuss unmet needs in the B-cell malignancy landscape.
Physician Preferences on BTKi
Mazyar Shadman, MD, MPH, and Jonathon Cohen, MD, MS, share their preferences regarding BTK-targeted treatment in B-cell malignancies.
ALPINE and ELEVATE-RR Trials
Two experts discuss use of ibrutinib and zanubrutinib and data from the ALPINE and ELEVATE-RR trials.
Zanubrutinib for B-Cell Lymphomas
Drs Shadman and Cohen review clinical trials of zanubrutinib in B-cell lymphomas.
Disease Progression and Resistance to BTK Inhibitors
Mazyar Shadman, MD, MPH, and Jonathon Cohen, MD, MS, talk about disease progression on BTKi and what mechanisms of resistance can occur.
Case 3: Disease Management Considerations
The panel of experts share their treatment recommendations for a 64-year-old woman with RET wild-type metastatic MTC.
ZETA and EXAM Clinical Trial Data
Dr Marcia Brose reviews key efficacy and safety data from the phase 3 ZETA and EXAM clinical trials.
Case 3: RET Wild-Type Metastatic MTC
Marcia Brose, MD, presents the case of a 64-year-old woman with RET wild-type metastatic medullary thyroid cancer.
The Future of DLBCL Treatment
Mazyar Shadman, MD, MPH, and Brian T. Hill, MD, PhD, consider potential treatment options for relapsed/refractory diffuse large B-cell lymphoma in the future.
Bispecific Antibody Therapy R/R DLBCL
Two experts examine bispecific antibody treatment use for relapsed/refractory diffuse large B-cell lymphoma.
Pralsetinib: MOA and ARROW Trial Data
Lori Wirth, MD, discusses the mechanism of action of pralsetinib and key data from the phase 1/2 ARROW clinical trial.
Selpercatinib: Clinical Practice Implications
The panel of experts discuss practical considerations regarding selpercatinib and the LIBRETTO-001 and LIBRETTO-531 clinical trial data.
Selpercatinib: MOA and LIBRETTO Trial Data
Lori Wirth, MD, discusses the mechanism of action of selpercatinib and key data from the LIBRETTO-001 and LIBRETTO-531 clinical trials.