Key opinion leaders review clinical cases in thyroid cancer, focusing on recent advances, treatment options, and clinical trials impacting clinical practice.
EP. 1: Case 1: RAI-Refractory DTC
Andrew Gianoukakis, MD, reviews the case of a 71-year-old woman with RAI-refractory differentiated thyroid cancer and the panel discuss relevant clinical trial data.
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EP. 2: Case 1: Considerations of RAI Use
Experts in thyroid cancer discuss treatment considerations surrounding the use of radioiodine therapy in patients with thyroid cancer.
EP. 3: Case 1: Treatment Considerations for Refractory DTC
Andrew Gianoukakis, MD, reviews the treatment and management options for a 71-year-old woman with RAI- refractory differentiated thyroid cancer.
EP. 4: RR-DTC: Definition and Clinical Presentation
The panel of experts share their insights into the definition and clinical presentation of radioiodine-refractory DTC.
EP. 5: RAI Treatment: Impact of Mutation Status
Experts in the management of thyroid cancer discuss radioactive iodine therapy and the clinical implications of mutational status in RAI- refractory DTC.
EP. 6: RR-DTC: Molecular Testing Considerations
Marcia Brose, MD and Lori Wirth, MD, discuss molecular testing considerations in patients with radioiodine-refractory DTC.
EP. 7: RR-DTC Systemic Therapy Considerations
Dr Andrew Gianoukakis, explores considerations surrounding systemic therapy in patients with RAI-refractory differentiated thyroid cancer.
EP. 8: Thyroid Cancer Treatment Guidelines
Andrew Gianoukakis, MD, reviews the NCCN guidelines for the treatment of patients with thyroid cancer.
EP. 9: DTC Key Efficacy and Safety Data
Dr Andrew Gianoukakis reviews the study design and key efficacy data of the phase 3 DECISION and SELECT trials.
EP. 10: SELECT Trial: Post-Hoc Analysis
Andrew Gianoukakis, MD, and Lori Wirth, MD, examine post-hoc analysis data from the phase 3 SELECT trial.
EP. 11: Lenvatinib: Dose Considerations
Marcia Brose, MD, discusses the efficacy and safety data of a phase 2 trial examining lenvatinib dose reductions in patients with RAI-DTC.
EP. 12: Case 2: RET+ Metastatic Medullary Thyroid Cancer
Lori Wirth, MD, presents the case of a 60-year-old man with RET+ metastatic medullary thyroid cancer.
EP. 13: TC Patient Considerations: Thyroidectomy
Lori Wirth, MD, and Andrew Gianoukakis, MD, discuss patient and clinical characteristics necessitating thyroidectomy in patients with thyroid cancer.
EP. 14: Case 2: RET+ MTC Disease Management
Dr Wirth reviews disease management considerations a 60-year-old man with RET+ metastatic medullary thyroid cancer.
EP. 15: Case 2: RET Mutations and Disease Management
The panel of experts discuss the importance of molecular testing and RET mutations in thyroid cancer disease management.
EP. 16: Case 2: Systemic Treatment Options
Experts in the management of thyroid cancer share their treatment recommendations for a 60-year-old man with RET+ metastatic medullary thyroid cancer.
EP. 17: Selpercatinib: MOA and LIBRETTO Trial Data
Lori Wirth, MD, discusses the mechanism of action of selpercatinib and key data from the LIBRETTO-001 and LIBRETTO-531 clinical trials.
EP. 18: Selpercatinib: Clinical Practice Implications
The panel of experts discuss practical considerations regarding selpercatinib and the LIBRETTO-001 and LIBRETTO-531 clinical trial data.
EP. 19: Pralsetinib: MOA and ARROW Trial Data
Lori Wirth, MD, discusses the mechanism of action of pralsetinib and key data from the phase 1/2 ARROW clinical trial.
EP. 20: Case 3: RET Wild-Type Metastatic MTC
Marcia Brose, MD, presents the case of a 64-year-old woman with RET wild-type metastatic medullary thyroid cancer.
EP. 21: ZETA and EXAM Clinical Trial Data
Dr Marcia Brose reviews key efficacy and safety data from the phase 3 ZETA and EXAM clinical trials.
EP. 22: Case 3: Disease Management Considerations
The panel of experts share their treatment recommendations for a 64-year-old woman with RET wild-type metastatic MTC.