An expert panel including two hematologist-oncologists and a pathologist center discussion on patient cases to review the optimal identification and management of blastic plasmacytoid dendritic cell neoplasm.
EP. 1: BPDCN: Epidemiology, Pathophysiology, and Diagnosis
Opening the discussion on the management of BPDCN, an expert panel consisting of two hematologist-oncologists and a pathologist, considers the causes, incidence and diagnostic approach to this rare disease.
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EP. 2: Identification and Classification of BPDCN
Shared insight on methods to identify blastic plasmacytoid dendritic cell neoplasm followed by updated classifications from the World Health Organization.
EP. 3: Patient Case 1: A 71-Year Old Man With BPDCN
Centering discussion on the first patient case of BPDCN, expert panelists highlight various assessment tools that may help overcome barriers to an early diagnosis.
EP. 4: A Role for Tagraxofusp in First-Line Setting in BPDCN
Expert perspectives on the first-line use of tagraxofusp, a CD123-directed therapy, in patients with blastic plasmacytoid dendritic cell neoplasm.
EP. 5: Management of Capillary Leak Syndrome in BPDCN
A brief review of the identification and management of capillary leak syndrome in patients being treated for blastic plasmacytoid dendritic cell neoplasm.
EP. 6: Factors in Selecting Optimal First-Line Therapy for BPDCN
Closing out their discussion on the first patient case of BPDCN, panelists consider which factors best inform the optimal selection of frontline therapy.
EP. 7: Patient Case 2: A 22-Year-Old Woman With BPDCN
Expert panelists review the case of a 22-year-old woman diagnosed with BPDCN and consider the role of first-line chemotherapy in this setting.
EP. 8: Patient Case 3: A 57-Year-Old Man With Relapsed BPDCN
Centering discussion on the third patient case, panelists review second-line therapy options for those who relapse with blastic plasmacytoid dendritic cell neoplasm.
EP. 9: Sequencing Therapy in BPDCN in the Second Line and Beyond
Comprehensive insight on the sequencing of agents in BPDCN management, followed by considerations for use of stem cell transplant in this setting.
EP. 10: Emerging Therapies in BPDCN
Shared insight on a number of novel therapies and treatment modalities being investigated in patients with blastic plasmacytoid dendritic cell neoplasm.
EP. 11: BPDCN: Future Directions in Care
Closing out their discussion on the management of blastic plasmacytoid dendritic cell neoplasm, expert panelists look toward the future treatment paradigm.