Kevin Halling, MD, PhD, discussed the clinical utility of RNA-sequencing methods in patients with cancer at the 2019 Association for Molecular Pathology Annual Meeting and Expo. Halling says RNA sequencing is a very powerful diagnostic technique.
Kevin Halling, MD, PhD, a consultant in the Division of Laboratory Genetics and Genomics and Department of Laboratory Medicine and Pathology at the Mayo Clinic, discussed the clinical utility of RNA-sequencing methods in patients with cancer at the 2019 Association for Molecular Pathology (AMP) Annual Meeting and Expo. Halling says RNA sequencing is a very powerful diagnostic technique.
According to Halling, these methods can be used to detect not only gene fusions in patients with cancer, but RNA sequencing can also detect point mutations and small indels. Additionally, pathologists can use RNA sequencing techniques to measure gene expression in the patient’s tumors.
ctDNA Detection Tied to Tumor Burden, Recurrence in HR+ Early Breast Cancer
December 13th 2024A phase 2 trial showed ctDNA detection in HR-positive early breast cancer was linked to larger tumors, higher residual cancer burden, and increased recurrence after neoadjuvant endocrine therapy.
Read More
Postoperative Radiation Improves HRQOL Over Endocrine Therapy in Breast Cancer
December 13th 2024In the phase 3 EUROPA trial, exclusive postoperative radiation therapy led to better health-related quality of life and fewer treatment-related adverse events in older patients with stage I luminal-like breast cancer at 24 months.
Read More