Promising Results for Bendamustine/Rituximab Plus Polatuzumab Vedotin in Lymphomas
Jonathon B. Cohen, MD, discusses findings from a study of polatuzumab vedotin, an anti-CD79b antibody-drug conjugate, with bendamustine and rituximab in patients with aggressive lymphomas.
Jonathon B. Cohen, MD, assistant professor in the Department of Hematology and Medical Oncology at Emory University School of Medicine, Winship Cancer Institute, discusses findings from a study of polatuzumab vedotin, an anti-CD79b antibody-drug conjugate, with bendamustine (Bendeka) and rituximab (Rituxan) in patients with aggressive lymphomas.
In this randomized phase II study, all patients received bendamustine/rituximab, and some patients were randomized to receive polatuzumab vedotin. Cohen says there was an impressive improvement in both progression-free survival and overall survival compared to the control arm, as well as higher complete response rates.
Examining the Non-Hodgkin Lymphoma Treatment Paradigm
July 15th 2022In season 3, episode 6 of Targeted Talks, Yazan Samhouri, MD, discusses the exciting new agents for the treatment of non-Hodgkin lymphoma, the clinical trials that support their use, and hopes for the future of treatment.
Listen
FDA Greenlights Treosulfan/Fludarabine Combo for AlloHSCT in AML and MDS
January 24th 2025The combination of treosulfan and fludarabine as a preparative regimen for allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia or myelodysplastic syndromes has been approved by the FDA.
Read More
