A Case of Estrogen-Driven Metastatic Breast Cancer
A Case of Estrogen-Driven Metastatic Breast Cancer
A 65-Year-Old Woman With Metastatic ER+/PR+ Breast Cancer
December 2013
- A 65-year-old woman was examined by her gynecologist after discovering a right-sided lump in her upper inner breast; she reported feeling exhausted lately, requiring frequent rest
- PE showed a grape-sized right palpable mass at 3 o’clock
- Diagnostic ultrasound showed a spiculated and hypoechoic mass measuring 26 x 23 x 21 mm; imaging in the left breast was unremarkable
- Core biopsy showed high-grade infiltrating ductal carcinoma
- Hormone receptor status: ER+/ PR+
- HER2,IHC 1+
- She underwent lumpectomy and axillary lymph node dissection that revealed a 2.3-cm infiltrating ductal carcinoma, 4 of 12 nodes were positive for disease
- CT of the chest, abdomen, and pelvis showed that the disease had spread to her bones and biopsy confirmed metastatic disease
- ECOG 1
- She was started on ribociclib + fulvestrant
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