Evaluating the Role of Liquid Biopsy in Breast Cancer
Aditya Bardia, MBBS, MPH, discusses the value of liquid biopsies in the treatment landscape of breast cancer. The real value of liquid biopsy in this space lies in providing oncologists with insight on what’s happening in tumor evolution.
Aditya Bardia, MBBS, MPH, a medical oncologist at Massachusetts General Hospital, discusses the value of liquid biopsies in the treatment landscape of breast cancer. The real value of liquid biopsy in this space lies in providing oncologists with insight on what’s happening in tumor evolution, says Bardia.
The use of liquid biopsies will improve upon the oncologist’s understanding of the disease and the patient at hand. With a better understanding of this, oncologists can give targeted therapies that target specific mutations, ultimately resulting in improved outcomes for these patients.
In May 2019, theFDA approved alpelisib (Piqray), a PI3K inhibitor, for the treatment of patients with HR-positive, HER2-negative,PIK3CA-mutated, advanced or metastatic breast cancer, following progression on or after an endocrine-based therapy.PIK3CAmutations are most common in patients with HR-positive breast cancer. Bardia says this agent is the beginning of the integration of precision medicine into breast cancer management.
Advancing Neoadjuvant Therapy for HER2+ Breast Cancer Through ctDNA Monitoring
December 19th 2024In an interview with Targeted Oncology, Adrienne Waks, MD, provided insights into the significance of the findings from the DAPHNe trial and their clinical implications for patients with HER2-positive breast cancer.
Read More
AI-Driven Deep Learning Model Shows Promise in Standardizing MDS Diagnosis
December 10th 2024In an interview, Palak Dave discussed how artificial intelligence, using deep learning to analyze bone marrow aspirate smear images, could standardize and accelerate the diagnosis of MDS vs pre-MDS conditions.
Read More
Systemic Therapy Choice Linked to Radiosurgery Outcomes in Brain Mets
December 6th 2024In an interview with Targeted OncologyT, Rupesh Kotecha, MD, discussed a study focused on how systemic therapy selection impacts outcomes in patients with brain metastases, particularly those with lung cancer.
Read More
