Surgery and Radiotherapy for Patients With Breast Cancer
Andrew D. Seidman, MD, from Memorial Sloan-Kettering Cancer Center, discusses breast cancer treatment with surgery and radiotherapy.
Andrew D. Seidman, MD, a professor of medicine at the Weill Cornell Cancer Center and an attending physician at the Memorial Sloan-Kettering Cancer Center, discusses breast cancer treatment with surgery and radiotherapy.
Seidman says that a study by Dr. Emiel J. Rutgers comes at a time when the oncology community has seen that it is possible to perform less surgery without putting patients at an increased risk of lymph node recurrence under the arm or in the axilla. In this study, patients with involvement of a sentinel lymph node were randomly assigned to undergo a complete axillary lymph node dissection or axillary radiotherapy.
Clinical Pearls
The findings from this trial showed that the two approaches were equally effective in controlling breast cancer recurrence, but the radiotherapy led to substantially less swelling of the arm and hand (lymphedema) 1 year and 5 years afterward. Seidman says this represents a new option for patients.
- Less surgery does not equate to an increased risk of lymph node recurrence
- In a trial, complete axillary lymph node dissection and axillary radiotherapy were equally effective in controlling breast cancer recurrence
Jhaveri Compares Safety and Duration of Adjuvant CDK4/6 Inhibitors in HR+ Breast Cancer
December 22nd 2024During a Case-Based Roundtable® event, Komal Jhaveri, MD, FACP, discussed dosing and toxicity concerns with the approved CDK4/6 inhibitor regimens used in the adjuvant setting for patients with hormone receptor–positive breast cancer.
Read More
Advancing Neoadjuvant Therapy for HER2+ Breast Cancer Through ctDNA Monitoring
December 19th 2024In an interview with Targeted Oncology, Adrienne Waks, MD, provided insights into the significance of the findings from the DAPHNe trial and their clinical implications for patients with HER2-positive breast cancer.
Read More
Breast Cancer Leans into the Decade of Antibody-Drug Conjugates, Experts Discuss
September 25th 2020In season 1, episode 3 of Targeted Talks, the importance of precision medicine in breast cancer, and how that vitally differs in community oncology compared with academic settings, is the topic of discussion.
Listen
