Dr. Peter Martin on Alternatives to Aggressive Therapy in Mantle Cell Lymphoma
February 5th 2016Peter Martin, MD, discusses the evolving paradigm of treatment for mantle cell lymphoma. Martin says the evolution of the paradigm currently includes Bruton's tyrosine kinase inhibitor, phosphoinositide 3-kinase inhibitor, immunomodulatory treatments, and immunotherapies.
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Dr. Darren Feldman on Treating Patients Who Develop Neutropenic Fever
February 4th 2016​Darren Feldman, MD, assistant attending physician for the Genitourinary Oncology Service, Memorial Sloan Kettering Cancer Center, discusses how to properly treat neutropenic fever as a toxicity stemming from chemotherapy treatment.
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Dr. Daniel Hamstra on the Benefits of Shorter Radiation Therapy Sessions for Prostate Cancer
February 4th 2016​Daniel Hamstra, MD, PhD, radiation oncologist, Texas Center for Proton Therapy, Texas Oncology, discusses the benefits of shorter radiotherapy treatment sessions for patients with prostate cancer.
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Dr. Matthew Cooperberg on New Aspects of the Treatment Paradigm for Prostate Cancer
February 3rd 2016Matthew Cooperberg, MD, genitourinary cancer specialist, University of California San Francisco, discusses the appropriateness of a more aggressive approach to men with high-risk prostate cancer. Cooperberg says currently, men will normally respond to surgery followed by adjuvant radiotherapy, as well as systemic therapy.
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Dr. Kenneth Wang on Forgoing Screening for Barrett's Esophagus
February 2nd 2016Kenneth Wang, MD, director of the Advanced Endoscopy Group and Esophageal Neoplasia Clinic, Mayo Clinic, discusses his opposition for Barrett's esophagus screening as a preventative measure for esophageal adenocarcinoma.
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Dr. Amy Heimberger on Better Imaging and Combination Therapies in Glioblastoma
January 30th 2016Heimberger says the treatment paradigm's future is two-pronged, in that it will consist of both combination therapies that activate the immune system and prevent immunosuppression, as well as understand CT and MRI scans of brain cancer patients.
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Dr. Keith Wilson on the Role of Helicobacter Pylori in Gastrointestinal Cancer
January 30th 2016<div style="color:#003668"><em>"When there is a mismatch between the human genetics and bacterial genetics, this may be one of the factors that leads to gastrointestinal cancer."<p align="right"><span style="color:#747474">- Keith Wilson, MD</span></em></div></p>
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Dr. David Reardon on Targeting Brain Tumors and Monitoring Resistances
January 29th 2016David Reardon, MD, clinical director, Center for Neuro-Oncology, Dana-Farber Cancer Institute, discusses identifying certain characteristics in a patient's brain tumor in order to administer better treatment.
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Dr. Susan Panullo on Optune Versus Salvage Chemotherapy in Glioblastoma
January 29th 2016Susan Panullo, MD, director, Neuro-oncology, director, Neurosurgical Radiosurgery, Weill Cornell Brain and Spine Center, discusses the improvement in quality of life in patients with glioblastoma treated with Optune (NovoTTF-100A).
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Dr. Eric Lim on the Diagnosis of Lung Cancer in Non-Smoker Patients
January 28th 2016Eric Lim, MD, consultant thoracic surgeon, Royal Brompton Hospital, Senior lecturer in thoracic surgery and reader, Imperial College London, discusses the decline in smoking not correlating to the current amount of lung cancer diagnoses.
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Dr. Georgia L. Wiesner on the Importance of Genetic Testing for Colorectal Cancer
January 27th 2016Georgia L. Wiesner, MD, MS, director, Clinical and Translational Hereditary Cancer Program, Ingram Professor of Cancer Research, professor of Medicine, cancer geneticist, Vanderbilt-Ingram Cancer Center, discusses the role genetic testing for colorectal cancer (CRC) plays in families.
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Dr. Charles M. Perou on the Evolution of Precision Medicine in Breast Cancer
January 26th 2016​Charles M. Perou, PhD, professor of Genetics, Pathology & Laboratory Medicine, Lineberger Comprehensive Cancer Center, UNC School of Medicine, discusses precision medicine in breast cancer and currently known biomarkers.
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Dr. Geoffrey Shapiro on the Role of CDK2 in Multiple Breast Cancer Types
January 26th 2016Geoffrey Shapiro, MD, PhD, director, Early Drug Development Center, Dana Farber, discusses the role of cyclin-dependent kinase (CDK4) in some breast cancer subtypes and the lack of targeted agents in triple-negative breast cancer.
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Dr. Anthony Mato on the Difference Between Intolerance and Resistance in CLL
January 22nd 2016Anthony Mato, MD, MSCE, director of the CLL Program, University of Pennsylvania, discusses the difference between intolerance and resistance when giving patients with chronic lymphotic leukemia ibrutinib.
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Dr. Cathy Eng on Bevacizumab Plus FOLFOXIRI for Patients With mCRC.
January 22nd 2016Cathy Eng, MD, FACP, medical oncologist, The University of Texas MD Anderson Cancer Center, discusses the combination of bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as a treatment for patients with metastatic colorectal cancer (mCRC).
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Dr. Cathy Eng on Bevacizumab Plus FOLFOXIRI for Patients With mCRC
January 22nd 2016Cathy Eng, MD, FACP, medical oncologist, The University of Texas MD Anderson Cancer Center, discusses the combination of bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as a treatment for patients with metastatic colorectal cancer (mCRC).
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Dr. John McCarty on Advice for Patients With Lymphoma Seeking Stem Cell Mobilization
January 22nd 2016​John McCarty, MD, medical director, Bone Marrow Transplant Program, Virginia Commonwealth University Health, discusses advice physicians can give to patients with lymphoma seeking stem cell mobilization.
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Dr. Aaron Logan on the Evolution of Immunotherapy in Oncology
January 21st 2016Aaron Logan, MD, PhD, discusses the evolving definition of immunotherapy and its importance within the realm of oncology. Logan says immunotherapies were initially meant try to vaccinate patients against their own tumors, though the methodologies involved did not prove successful.
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Dr. Ashani T. Weeraratna on Aging and its Effects on How Melanoma Progresses and is Treated
January 21st 2016Ashani T. Weeraratna, PhD, discusses the similarities in treatment between younger and older patients with melanoma. She says this lack of differentiation between treatment regimens could pose a problem in the future. One such issue is that older patients tend to react less well to treatments like vemurafenib.
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Dr. Geoffrey R. Oxnard Treating EGFR-Inhibitor Resistant Patients With Lung Cancer
January 18th 2016Geoffrey R. Oxnard, MD, discusses resistance to EGFR inhibitors in patients with lung cancer. Oxnard says resistance to treatment in lung cancer is complex, in that it can change from day to day. He cites one example as patients possibly being resistant to T790M targeted treatments to possibly a MET-related resistance.
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Marianne Davies, NP, on Assessing Immunotherapy Toxicities in Lung Cancer Patients
January 18th 2016Marianne Davies, NP, discusses making patients' oncology team their first line of contact should they develop any toxicities related to receiving treatment. Davies says this is important for patients so that the oncology team can assess whether it is an immune-related side effect, or an issue that can be dealt with by their primary care physician.
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Dr. Tomasz M. Beer on BRCA Gene Defects in Advanced Prostate Cancer
January 16th 2016Beer says that while BRCA is normally associated with breast cancer, the gene is found in up to 20% of advanced prostate cancers. He says of this 20% patient population, roughly half inherit the BRCA gene and the other half acquire it.
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Dr. Toni Choueiri on Nivolumab and Cabozantinib Becoming First-Line Therapies in RCC
January 14th 2016Choueiri says that while both drugs have a chance to become first-line therapies, nivolumab does more so than cabozantinib. He says there is a phase III study that has recently finish accrual that looks at combining nivolumab and ipilimumab, in comparison to sunitinib, as a treatment for RCC.
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